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If a death signal comes from inside, this enzyme is activated
This is released by mitochondrion in apoptosis
How does internal apoptosis happen?
- CytC-Apaf1 complex
- caspase 9
What are the ingredients of an apoptosome?
This prevents release of Cyt C
How does external apoptosis happen?
- Caspase 8
A receptor which binds a death ligand but doesn’t work
- decoy receptor
- too much of it in tumors
This stuff promotes mitosis
This stuff inhibits mitosis by blocking activation of Rb
What does an APC do?
Makes sure spindle fibers is attached to centromeres
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