MM19

Card Set Information

Author:
Bobopudge
ID:
67425
Filename:
MM19
Updated:
2011-02-19 09:51:53
Tags:
MM
Folders:

Description:
Cell death
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  1. If a death signal comes from inside, this enzyme is activated
    Caspase 9
  2. This is released by mitochondrion in apoptosis
    cytochrome c
  3. How does internal apoptosis happen?
    • CytC-Apaf1 complex
    • caspase 9
  4. What are the ingredients of an apoptosome?
    • Cyt C
    • Apaf-1
    • Caspase 9
  5. This prevents release of Cyt C
    Bcl2
  6. How does external apoptosis happen?
    • Fas-Fas
    • Trimerization
    • FADD
    • Caspase 8
  7. A receptor which binds a death ligand but doesn’t work
    • decoy receptor
    • too much of it in tumors
  8. This stuff promotes mitosis
    • growth factors
    • EGF
  9. This stuff inhibits mitosis by blocking activation of Rb
    TGF-B
  10. What does an APC do?
    Makes sure spindle fibers is attached to centromeres

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