Tiff Ch17

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micro
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Tiff Ch17
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2011-02-21 22:32:56
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Tiff Ch17
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  1. Defenses against any pathogen.
    Innate Immunity (non-specific)
  2. Specific antibody and lymphocyte response to an antigen; developed during the lifespan:
    Adaptive Immunity (specific)
  3. ___ observed immunity in chickens injected with weakened pathogens.
    Pasteur
  4. __ ___ received the Nobel Prize for development of antitoxin.
    Von Behring
  5. ___ work led to the identification of antibodies in serum.
    Ehrlich’s
  6. A substance that causes the body to produce specific antibodies or sensitized T cells:
    Antigen (Ag)
  7. Proteins made in response to an Ag; can combine with that Ag.
    Antibody (Ab)
  8. Serum proteins that bind to Ab in an Ag–Ab reaction; cause cell lysis.
    Complement
  9. Infants get their ___ immunity from breast milk.
    adaptive
  10. ___ immunity involves antibodies produced by B cells.
    Humoral
  11. _ __ recognize antigens by antibodies on their surfaces.
    B cells
  12. HumorAl has an "A" in it which you could use to remember ___ – antiBodies has a "B" in it which you can link to __ cells or ___ ___.
    antibodies / B / bone marrow
  13. Cell-mediated immunity involves __ cells.
    T
  14. T cells recognize ___ by TCRs on their surfaces.
    antigens
  15. The study of reactions between antibodies and antigens.
    Serology
  16. The generic term for serum because it contains Ab.
    Antiserum
  17. Serum proteins
    Globulins
  18. Antibodies
    Immunoglobulins
  19. Serum fraction containing Ab.
    Gamma globulin
  20. ___ recognize and react with antigenic determinants or epitopes on an antigen.
    Antibodies
  21. Antibodies tend to work in ___.
    pairs
  22. A substance of low molecular weight that does not cause the formation of antibodies by itself but does so when combined with a carrier molecule.
    Hapten
  23. -% of total serum antibody: 80%
    -Fix complement
    -In blood lymph and intestine
    -Cross placenta
    -Half-life = 23 days
    IgG
  24. -% of total serum antibody: 5-10%
    -Fix complement
    -In blood, lymph, and on B cells
    -Does not cross placenta
    -Half-life = 5 days
    IgM
  25. -% of total serum antibody: 10-15%
    -No fix complement
    -In secretions
    -Does not cross placenta
    -Half-life = 6 days
    IgA
  26. -% of total serum antibody: 0.2
    -No fix complement
    -In blood, lymph, and on B cells
    -Does not cross placenta
    -Half-life = 3 days
    IgD
  27. -% of total serum antibody: 0.002
    -No fix complement
    -On mast cells, basophils and in blood
    -Does not cross placenta
    -Half-life = 2 days
    IgE
  28. What is the function of the IgG antibody?
    Enhances phagocytosis; neutralizes toxins and viruses; protects fetus and newborns
  29. What is the function of the IgM antibody?
    gglutinates microbes; first Ab produced in response to infection which is helpful in diagnosis of an infection.
  30. What is the function of the IgA antibody?
    Mucosal protection
  31. What is the function of the IgD antibody?
    On B cells, initiate immune response
  32. What is the function of the IgE antibody?
    Allergic reactions; lysis of parasitic worms; EOSINOPHILS!
  33. The natural programmed death of a cell; the residual fragments are disposed of by phagocytosis:
    Apoptosis
  34. Auto-immune diseases can develop when there is an issue with ___ ___.
    clonal deletion
  35. The process of destroying B and T cells that react to self antigens:
    Clonal deletion
  36. The strength of the bond between an antigen and an antibody is called ___.
    affinity
  37. Antibody recognizes a specific epitope:
    Specificity
  38. Naturally acquired active imunity results from ___.
    infection
  39. Naturally acquired passive immunity is transferred ___ ___ or thru ___.
    cross placenta / colostrum
  40. Artificially acquired active immunity results from an ___.
    immunization

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