Ch1 basic concepts in immunology

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Ch1 basic concepts in immunology
2011-02-21 23:03:28

Test 1
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  1. Pluripotent Hematopoetic cell
    • -located in the bone marrow
    • -where all the cellular elements of the blood including the cells of the immune system arise from
  2. Common Myeloid cell
    precursor of the macrophages, granulocytes, mast cells, and dendritic cells of the innate immune system and also of megakaryotes
  3. Common Lymphoid cell
    • -progenitor cell
    • -stem cells that give arise to all lymphocytes. They are derived from pluripotent hematopoietic stem cells
  4. Co stimulatory molecule
    Molecules that provide signals that act together with antigen to stimulate T cells
  5. Cells with pathogen associated molecular pattern (PAMPs)
    • present in cells of microorganisms
    • -helps innate immune system to distinguish self from non self(pathogen)
    • -recognized by pattern recognition receptors (PRRs) of the immune system
  6. B lymphocytes (B-cells) and T lymphocytes (T-cells)
    Each lymphoid progenitor gives rise to a large number of lymphocytes, each bearing a distinct antigen receptor
  7. Constant and Variable Region
    antibody molecules secreted by the b are composed of two regions
  8. During a lymphocyte, one member of each set of gene segments is joined randomly to the others
  9. Periarteriolar lymphoid sheath
  10. Where B cell differentiate into plasma cells
  11. Primary vs. Secondary response