neuro cancers

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Author:
fischer_april123
ID:
68095
Filename:
neuro cancers
Updated:
2011-02-22 09:21:32
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neurology cancers
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neurology cancers
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  1. Most common adult primary brain tumor. Grave prognosis (<1 year life expectancy) Found in both hemispheres because it can cross the corpus callosum (like a butterfly-butterfly glioma). Stains positive for GFAP (astrocyte marker)
    Glioblastoma Multiforme
  2. Second most common adult primary brain tumor. Often occurs in convexities of hemispheres and parasagittal region. Arises from arachnoid cells external to brain. Resectable.
    Meningioma
  3. Third most common adult primary brain tumor. Schwann cell origin-often localized to CN VIII. Resectable
    Schwannoma (acoustic schwannoma)
  4. Relatively rare, slow growing brain tumore. Most often in frontal lobes. Chicken wire capillary pattern
    Oligodendroglioma
  5. Most commonly prolactinoma. Bitemporal hemianopia (due to pressure on optic chiasm) and hyper/hypo-pituitarism are sequelae.
    Pituitary adenoma
  6. Usually well-circumscribed. In children most often found int the posterior fossa. May be supratentorial. GFAP positive. Benign, good prognosis
    Pilocytic (low-grade) astrocytoma
  7. Highly malignant cerebellar tumor more common in children. A from of primative neuroectodermal tumor (PNET). Can compress 4th ventricle, causing hydrocephalus.
    Medulloblastoma
  8. Ependymal cell tumors most commonly found in the 4th ventricle; can cause hydrocephalus. Poor prognosis. More common in children
    Ependymoma
  9. Most often cerebellar and in kiddos; associated with von Hippel-Lindau syndrom when found with retinal angiomas. Can produce EPO causing polycythemia
    Hemangioblastoma
  10. Benign childhood tumor confused with pititary adenoma (can cause bilat hemianopia). Most common childhood supratentorial tumor.
    Craniopharyngioma.
  11. Pseudopalisading pleomorphic tumor cells--border central areas of necrosis and hemorrhage
    Glioblastoma Multiforme
  12. spindle cells concentrically arranged in a whorled pattern; psammoma bodies (laminated calcifications)
    Meningioma
  13. Bilat tumor found in neurofibromatosis type 2
    Schwannoma
  14. "fried egg" cells-round nuclei with clear cytoplasm (halos) often calcified
    Oligodendroglioma
  15. Derived from Rathke's pouch
    Pituitary adenoma
  16. Rosenthal fibers--eosinophilic, corkscrew fibers
    Pilocytic astrocytoma
  17. Rosettes or perivascular pseudorosette pattern of cells. Radiosensitive
    Medulloblastoma
  18. Chracteristic perivascualr pseudorosettes. Rod-shaped blepharoplasts (basal ciliary bodies) found near nucleus.
    ependymoma
  19. foamy cells and high vascularity are characteristic
    hemangioblastoma
  20. derived from remnants of rathke's pouch. Calcification is common (tooth enamel-like)
    Craniopharyngioma

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