Glycolysis – glucose breakdown (2 ATP), Krebs Cycle (2 ATP), Oxidative phosphorylation (26-28 ATP). 30-32 ATP total per glucose molecule.
Active transport examples, details?
Ca2+ pumps – Ca2+ binds to carrier protein in cytosol, carrier protein is phosphorylated by ATP -> ADP + Pi, carrier protein changes shape moving Ca2+ out of cell (where concentration is greater).
Na+/K+ ATPase – pumps 3 Na+ out of cell and 2 K+ into cell simultaneously to generate gradients for electrical impulses in nerves and muscles AND drive co-transport of other substances across the membrane (glucose)
Structural classification of neurons w/ location.
Bipolar (sensory in eyes/ears/nose)
PNS - Forms myelin sheath (single axon)
PNS - Surrounds cell bodies in ganglia
CNS - Forms myelin sheath (mutiple axons)
CNS - Varied functions, controls permeability of blood-brain barrier
CNS - Act as macrophages
CNS - Line brain ventricles/spinal cord cavities, creates CSF
Nicotinic ACh Receptors: Ionotropic/Metabotropic?
Nicotinic ACh Receptors: Excitatory/Inhibitory?
Nicotinic ACh Receptors: Location?
Found in specific regions of brain, skeletal muscle cells, cell bodies of autonomic motor neurons in ganglia
Nicotinic ACh Receptors: Function?
Na+ in and K+ out simultaneously
Nicotinic ACh - Neurotransmitter removal?
ACh quickly broken down by acetyl cholinesterase which is embedded in the post-synaptic cell membrane
Muscarinic ACh receptors: Ionotropic/Metabotropic?