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The study of what happens to a drug from the time it is put in to the body until the parent drugand all metabolites have left the body.
Taking all doses of medications correctly over prescribed length of therapy
Failure to follow directions
Lack of knowledge
an inactive (inert) substance
the transferring of responsibility for the performance of an activity or taskwhile retaining accountability for the outcome.
THE TASK IS DELEGATED NOT THE PATIENT
5 rights of delegation
Drug enters blood stream
Drug circulates through body
Drug broken down into metabolites- usually in liver
Drug eliminated from body
time 1/2 drug eliminated from body - important for dosing time.
Factors affecting drug action
Age, weight, gender, dosage, route, food and drug interactions, genetics and race, pathologic conditions, psychological
Drug A & B (similuar effects)
Drug A & B (Different actions) greater than effect of single drugs.
More than doubled.
Drug A displaces Drug B from plasma protein binding sites- more free drug B-
greater effect of drug B
Drug A interfers with excretion or metabolism of Drug B- Drug B
in body longer
- increase effect of Drug B
Molecules move with the concentration gradient (greater to lesser)until equilibrium is reached
Molecules move against the concentrated gradient
The study of what drug does to the body. How the drug works.
The Four Phases
When the drug begins to work
Drug at highest blood level-most amount of drug available ot go to target tissues.
Length of time
Angiotestin Converting Enzyme
High concentration of drug in bloodstream
decreased responce to drug
Drugs interact to increase the effect of one or both drugs
Effects of drugs
Stimulate Body Functions
Depress Body Functions
Replace Body Functions
attach to a receptor
to cause a response
Attach to a receptor
to block a response
need to continue to prevent
compulsive need to use substance
disease process characterizied by continued use of a specific psychoactive substance