Pharm Chap 6 *

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Author:
vongc2
ID:
68287
Filename:
Pharm Chap 6 *
Updated:
2011-02-22 21:59:17
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Pharm Chap
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Description:
Sedative-Hypnotic and Antianxiety Agents
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  1. What are Benzodiazipines used for? (2)
    Can they cause tolerance?
    what is the suffix?
    • 1. to relax and promote sleep; exert hypnotic effects
    • yes it can cause tolerance
    • pam, lam
  2. list 5 Hypnotic agents Benzodiazipines
    • Temazepam (restoril)
    • Triazolam (halcion)
    • Estazolam (ProSom)
    • Quazepam (Doral)
    • Flurazepam (Dalmane)
  3. Name 5 Anti-Anxiety Agents of Benzodiazipines
    • Diazepam (Valium)
    • Alprazolam (Xanax)
    • Clonazepam (Klonopin)
    • Lorazepam (Ativan)
    • Halazepam (Paxipam)
  4. Which GABA receptors cause inhibition by increasing cloride ion entry?
    GABAA and GABA C
  5. Which GABA receptor causes inhibition by increasing potassium efflux?
    GABAB
  6. Benzodiazepines act primarily on which GABA receptor?
    • GABAA receptor
    • Hence, benzodiazepines = GABAA agonists
  7. Name 3 nonbezodiazepine sedative-hypnotics.
    • Zolpidem (ambien)
    • Zaleplon (Sonata)
    • Alcohol
  8. T/F benzodiazepines and nonbenzodiazepines are usually highly lipid soluble.
    Ture
  9. Name 1 residual effect of taking benzodiazepines and nonbenzodiazepines.
    Anterograde amnesia-
  10. T/F Benzodiazepines and nonbenzodiazepines can cause drug tolerance, dependence and withdrawl.
    true.
  11. Withdrawl after short-term use may cause sleep disburbances
    what is "rebound insominia"
  12. Need to take more of a drug to have the same effect
    What is "drug tolerance"
  13. Onset of withdrawal if drug administration is ceased
    What is "Dependence"?
  14. 1.Buspirone
    2. Benzodiazepine?
    3. What does it do?
    4. tolerance and dependence?
    • 1.(Buspar)
    • 2. No
    • 3. serotonin agonist
    • 4. small risk of tolerance and dependence
    • *has moderate efficacy
  15. 1. Name a beta-adrenergic antagonist.
    2. What does it do?
    3. give example.
    • 1. beta blockers
    • 2. decreases anxiety without producing sedation
    • 3. Propranolol (Inderal)

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