Pharm Chap 6 *
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What are Benzodiazipines used for? (2)
Can they cause tolerance?
what is the suffix?
- 1. to relax and promote sleep; exert hypnotic effects
- yes it can cause tolerance
- pam, lam
list 5 Hypnotic agents Benzodiazipines
- Temazepam (restoril)
- Triazolam (halcion)
- Estazolam (ProSom)
- Quazepam (Doral)
- Flurazepam (Dalmane)
Name 5 Anti-Anxiety Agents of Benzodiazipines
- Diazepam (Valium)
- Alprazolam (Xanax)
- Clonazepam (Klonopin)
- Lorazepam (Ativan)
- Halazepam (Paxipam)
Which GABA receptors cause inhibition by increasing cloride ion entry?
GABAA and GABA C
Which GABA receptor causes inhibition by increasing potassium efflux?
Benzodiazepines act primarily on which GABA receptor?
- GABAA receptor
- Hence, benzodiazepines = GABAA agonists
Name 3 nonbezodiazepine sedative-hypnotics.
- Zolpidem (ambien)
- Zaleplon (Sonata)
T/F benzodiazepines and nonbenzodiazepines are usually highly lipid soluble.
Name 1 residual effect of taking benzodiazepines and nonbenzodiazepines.
T/F Benzodiazepines and nonbenzodiazepines can cause drug tolerance, dependence and withdrawl.
Withdrawl after short-term use may cause sleep disburbances
what is "rebound insominia"
Need to take more of a drug to have the same effect
What is "drug tolerance"
Onset of withdrawal if drug administration is ceased
What is "Dependence"?
3. What does it do?
4. tolerance and dependence?
- 2. No
- 3. serotonin agonist
- 4. small risk of tolerance and dependence
- *has moderate efficacy
1. Name a beta-adrenergic antagonist.
2. What does it do?
3. give example.
- 1. beta blockers
- 2. decreases anxiety without producing sedation
- 3. Propranolol (Inderal)
What would you like to do?
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