The second form of molecular control:
o If the environment, for example, provides all the tryptophan the cell needs, the cell stops making the enzymes that catalyze the synthesis of tryptophan
§ In this case, the control of enzyme production occurs at the level of __, the synthesis of mRNA coding for these enzymes.
§ More generally, many genes of the bacterial genome are switched on or off by changes in the metabolic status of the cell.
§ The basic mechanism for this control of __in bacteria, described as the __, was discovered in 1961 by François Jacob and Jacques Monod at the Pasteur Institute in Paris.
- gene expression
- operons model