Neuroscience exam 2 slide 13

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ankurkum
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69586
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Neuroscience exam 2 slide 13
Updated:
2011-02-28 14:05:02
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  1. How does large changes in membrane potential caused by?
    • small change in ionic concentrations
    • -the number of ions that need to move to generate a potential is very small
    • -concentrations remain essentially constant
  2. How to determine structure of K+ channel?
    • by X-ray crystallography
    • -negatively charged amino acid around pore which attract positive ions
  3. Process of K+ ion to enter selectivity filter .
    • K+ ion must lose all water molecules to enter
    • -oxygen atoms in selectivity filter spaced perfectly to serve as replacement foroxygen atoms in water molecules stripped off
  4. How does Na+ ion do in selectivity filter?
    • Na+ ion can not enter, even though it's smaller
    • -oxygen atoms in selectivity filter too far away to compensate for energy loss of water molecules

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