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True or False?
Deoxynucleotides are made from the reduction of ribonucleoside monophostphates.
- False.
- They are made from the reduction of diphosphates.
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What enzyme catalyzes the reduction of ribonucleosides?
Ribonucleotide Reductase.
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Identify what each of the following ribonucleosides are converted to following catalysis by ribonucleotide reductase: CDP, UDP, GDP, ADP.
- 1.) dCDP
- 2.) dUDP
- 3.) dGDP
- 4.) dADP
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How is Thymine synthesized for use in DNA?
Thymidylate synthase converts dUMP to dTMP.
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What does thymidylate synthase do to dUMP to convert it to dTMP?
It transfers a methyl-group from tetrahydrofolate (N5,N10 - mehtylenetetrahydrofolate) to the dUMP.
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