Methylxanthines/Psychomotor Stimulants

Card Set Information

Author:
Anonymous
ID:
70436
Filename:
Methylxanthines/Psychomotor Stimulants
Updated:
2011-03-03 11:34:23
Tags:
caffeine ADHD
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Description:
caffeine and ADHD
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  1. Caffeine
    • Trimethylxanthine found in coffee, tea, and OTC's; an adenosine competative antagonist (inhibits the inhibitor), phosphodiesterase inhibitor (both actions allow increase in cAMP)
    • High doses cause jitteriness, tremors; can exacerbate anxiety and sleep disorders
    • Produces dependence
  2. Theophylline
    • Dimethylxanthine similar to caffeine
    • Greater ratio of peripheral to central effects
  3. Theobromine
    Dimethyxanthine similar to caffeine; found in CHOCOLATE
  4. d-amphetamine (Dexedrine)
    • ADHD, weight control, narcolepsy/ stimulates dopamine and NE release
    • When used for weight control, tolerance develops
    • In ADHD SE include anorexia and insomnia
  5. Cocaine
    • Inhibits DA uptake, but effects very similar to amphetamines
    • Used RARELY in medicine as a local anesthetic; metabolized by plasma esterases
  6. Methylphenidate (Ritalin & Concerta)
    ADHD/ Narcolepsy; Stimulates DA release, effects similar to amphetamines

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