GE15

The flashcards below were created by user Bobopudge on FreezingBlue Flashcards.

  1. What is the equation for GFR?
    Image Upload
  2. What is the equation for Creatinine Clearance?
    Image Upload
  3. What is the equation for Dosing Rate?
    Image Upload
  4. Time for plasma concentration of drug to be reduced by 50%
    Half-life
  5. When the ellimination of a drug = availability
    • Steady state
    • it takes 4-5 half-lives to reach this
  6. Fraction of the drug that enters systemic circulation (B-word)
    Bioavailabilty
  7. Giving a big dose in the beginning to reach therepeuttic window faster
    Loading dose
  8. What is the equation for Loading Dose?
    • Image Upload
    • LD: Loading Dose
    • Target Cp: Target plasma concentration
    • Vss: Volume of distribution in steady state
    • F: Bioavailability
  9. What is the equation for Maintenance Dose?
    • MD = Target Cp x CL / F
    • MD: Maintenance dose
    • Target Cp: Target plasma conc
    • CL: clearance
    • F: Bioavailability
Author:
Bobopudge
ID:
70677
Card Set:
GE15
Updated:
2011-03-27 15:55:04
Tags:
GE Kidney Drug elimination Kevin
Folders:

Description:
Drug Elemination
Show Answers: