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  1. Caffein, cranberry juice, and alcohol have this in common
    They're natural diuretics
  2. What two things do u use diuretics to treat?
    • Edema
    • Hypertension
  3. Image Upload 1
    • 1.Loop diuretics
    • 2.Thiazides
    • 3.K sparing drug
    • 4.Osmotic diuretics
    • 5.Carbonic anhydrase inhibitors
  4. This word means very powerful diuretic
    • High ceiling
    • **Loop diuretics have the highest one
  5. These drugs inhibit Na/K/Cl co-transporters in the ascending loop.
    • Loop diuretics
    • What Im saying is it inhibits their reabsorption
  6. What are 3 side effects of diuretics
    • hypokalemia
    • hypovolemia
    • hypotension
    • ***hypochlorimic metabolic acidosis
    • ****hyperuricemia
  7. This class of diuretics inhibit Na/Cl co-transporter in the distal tubule
  8. 2 modes of action of K-sparing drugs:
    Image Upload 2
  9. What are side effects of K-sparing drugs?
    • Hyperkalemia
    • Acidosis
    • Gynomastia
    • Menstrual cycle abnormalities
  10. A hydrophilic thingy which is filtered through the nephron, taking water along with it (like a sponge)
    Osmotic diuretic
  11. This diuretic blocks carbonic anhydrase in the proximal tubules.
    • Carbonic anhydrase inhibitors
    • So really it stops the making of bicarbonate and hydrogen.
    • So in the end it stops reabsorption of Na+ by cotransport and can cause acidosis.
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