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In a suprainfection the _____flora is _____, by _________ antibiotics causing ________infections, and nonsuseptible organisms to ________.
T/F bacterialcidal is reversible and bacterialstatic is irreversible
False...bacteriacidal kills, stactic slows or inhibits growth
T/F gram positive are faculative cocci
True...they can live with or with out oxygen
Effective plasma concentrations are affected by ADME...what does that stand for?
It was stated that ___% of oral infections were caused by gram positive microorganisms....but it is not so...oral infections are caused by _______ faculative cocci and _______bacilli, by the time antibiotics are indicated it is mostly anerobic gram neg bacilli that predominate
FYI this is a Polymicrobial infection...party in the mouth, until some microbes decide its mostly exclusive..
- Gram positive
- gram negative
Most odontogenic infections are caused by 3 types of micoroorganisms
- anerobic gram-positive cocci
- gram neg bacilli
- faculative gram positive cocci
The oral enviroment of an adult harbors more than ____ bacterial species.
The predominate flora creates an_______ of synergism by ________oxygen and creating _________, making the mouth more acidic, which supports _______bacteria. This facilitates selective bacterial survival.
bacterial species ______ as the infection matures or is clinically manifests as either ________ or Chronic conditions.
chronic infections may ____ ___ and become fiborus, which may make it hard for the antibiotic to reach it. making it necessary for debridement.
T/F acute infections are more likely to spread cause the immune system can't get it controlled as quickly
Yep its true
T/F Chronic infections tend to be more localized, unless the immune response is overwhelmed.
T/F If optimal debridment occurs and the immune system is competent there is often no need for antibiotics.
T/F antibacterial agents can destroy all bacteria
False...don't expect them to.
T/F corticosteriods enhance the immune response
False- it suppresses the response and masks clinical signs of infection and Lymphocyte function is reduced
T/F If a pt is immunocompromised it is not indicated to give them a antibiotic
False- give it to them!
__________ drugs interupt cell wall synthesis. ________, _________,and __________ are bacteriacidal drugs
T/F metronidazole (Flagyl) inhibits DNA and leads to cell death in anaerobes.
True...isn't this what they use in bacterial vaginitis???
Bactericidal drugs target ______ pathways essential for survival. Bacteriostatic drugs target metabolic pathways necessary for ______ not survival.
bacteriostatic drugs are?
•Erythromycin, clindamycin, tetracycline