MD/SMA

Card Set Information

Author:
Anonymous
ID:
71176
Filename:
MD/SMA
Updated:
2011-03-06 22:02:29
Tags:
Pathophys
Folders:

Description:
Pathophys Test 2
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user Anonymous on FreezingBlue Flashcards. What would you like to do?


  1. group of inherited disorders characterized by degeneration of skeletal muscle
    Muscular Dystrophy
  2. MD is the result of a metoblic deficit of _______ resulting in cell degeneration and necrosis.
    dystrophin
  3. true or false: few muscular dystrophies are inherited and involve a mutation in genes
    false: all involve inheritance and gene mutation
  4. Can MD be caused by spontaneous mutations?
    yes
  5. MD is more common for _____, primarily of the Duchenne or Becker variety
    males
  6. 3 routes of MD inheritance
    • Autosomal dominant
    • Autosomal recessive
    • X linked recessive
  7. For MD, muscle fibers are replaced with____ & ______ ______ tissue, leading to hypertrophic appearance of muscle
    fat & fibrous connective tissue
  8. this holds the cytoskeleton to the extracellular matrix
    dystrophin
  9. Duchenne's MD inheritance is _______ with age of onset at __ to __ years. Parts of the body affected are ___, _____, & _______ with ______ progression.
    • X-linked recessive
    • 2-3 years
    • hips, legs & shoulder girdle
    • rapid
  10. Fascioscapula humeral MD has _____ inheritance, age of onset before _____, affects _______, ______, & _______ with ______ to _________ progression
    • autosomal dominant
    • before 20
    • shoulder neck and face
    • slow to moderate
  11. Myotonic MD has ______ inheritance and can occur from _____ to _______. It affects the ______ & ______ and progresses ______.
    • autosomal dominant
    • birth to 50 years
    • face & hands
    • slow
  12. Limb girdle MD has ______ inheritance and can affect _____ ages. It affects the _____ & _______ with _______ progression
    • autosomal recessive
    • all ages
    • shoulder & pelvis
    • varied

What would you like to do?

Home > Flashcards > Print Preview