Card Set Information
Name the five WBC
What are the two lineages of Hematopoietic stem cells (HSC's)?
: Macrophages, Granulocytes, RBC, platelets
: T-cells, B-cells, NK cells
What are three important cytokines?
What does IL-3 and IL-7 form?
Lymphoid stem cells
What does IL-3 + GM-CSF form?
What is the difference b/t inducible and constituitive hematopoiesis?
: ramp up production due to injury
: Constant production
What CD is crucial for bone marrow transplants?
How does antigen presentation work?
-Break down protein and expose antigen on surface of cell
What is necessary for activation of T-cells?
Antigen presentation (APCs)
What molecules display antigens on cells?
What four cells utilize APC?
What are two common dendritic cells and where are they found?
What are the three granulocytes?
When there are immature Neutrophils due to chronic infection or toxicity
What is Neutropenia?
<1000 cells (normal is 1800-7700)
What is Neutrophilia?
>8000 cells (normal 1800-7700)
What is Eiosinophilia?
What two cells can stimulate Eiosinophils?
Basophils and Mast Cells
What are the three destructive enzymes of Eiosinophils?
MBC, ECP, EPO
What is the difference b/t an effector and a memory cell?
: used now
: used later when needed
What is the main diff b/t T-cell and NK cell?
activated by cells with MHC
activated by cells w/o MHCI
% monocytes in blood
% PMN in blood
% eiosinophils that are leukocytes
% basophils that are leukocytes
What granulocytes are activate by complement factor C3a?
Basophils and Mast cells
% lymphocytes that are leukocytes
20% - 30%
% Lymphocytes that are B
% lymphocytes that are T
What cell is a major target of HIV and why?
because of the high immunity it provides through its CD4 marker