antihypertensives

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  1. what are the 2 factors that, when altered, can cause increase/decrease in BP?
    • cardiac output (HR, contractility, blood volume, venous return)
    • peripheral resistance (arteriolar constriction)
  2. significance of sympathetic baroreceptor reflex? where are the two receptors located?
    • a system that regulates BP via the sympathetic NS by activating heart & vessel receptors
    • two baroreceptors are located in the carotid sinus & aortic arch
  3. describe the renin-angiotensin-aldosterone system.
    • 1. increased BP triggers kidneys to release renin
    • 2. renin turns angiotensinogen to angiotensin I
    • 3. ACE (angiotensin converting enzyme) catalyzes angiotensin I to angiotensin II
    • 4. angiotensin II constricts blood vessels, causing increased BP
    • 5. angiotensin II also triggers release of aldosterone
  4. how do the kidneys play a role in BP?
    • 1. BP falls, and the kidney reabsorbs sodium, water, and potassium
    • 2. reabsorption causes increased blood volume
    • 3. increased blood volume causes increased venous return
    • 4. increased venous return causes increased CO
    • 4. increased CO causes rise in BP
  5. the kidney's effect on BP is neutralized by using ____ (what medication?)
    diuretics
  6. main action of sympatholytics? (antiadrenergics)
    affect the sympathetic nervous system (heart or blood vessels) to decrease BP
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71469
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antihypertensives
Description
drugs for hypertension - pharm quiz 2
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