LAB 18A Lymphatic 2.txt

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TomWruble
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71615
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LAB 18A Lymphatic 2.txt
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2011-03-08 14:31:58
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  1. Cite differentiating characteristics:
    • Lymph
    • Trabecula which seperate follicle chambers around the afferent vessel perimeter
    • Medulary cords and sinuses in the center and toward the efferent (1 or 2) vessels
  2. Name 2 functions of this organ
    • Spleen - There are no trabeculae in the spleen
      1. "White Pulp" contains lumphocytes responsible for the immun functions of the spleen.
      2. Macrophages in the "Red Pulp" remove worn out RBCs, debris, bacteria, viruses, and toxins from blood flowing through.
  3. Name 2 functions of this organ
    • Lymph node: 1) filtering through T & B-cells,and 2) filtering through macrophages.
      • Follicles and within them a globular mass called a germinal center which contains rapidly dividing B-cells. The remainder of the follicle area is T-cells.
      • Trabecula
      • Subcapsular sinus
      • Capsule
      • Medullary cords - containing macrophages
      • Medullary sinuses
  4. All lymphoid tissue (except these?) contains T & B-cells:
    Thymus & Bone Marrow
    • Lymph Node
      • Spleen
      • Shown: Capsule with Red Pulp & White Pulp
      • Lymphocytes are suspended in White Pulp and are responsible for the immune functions of the spleen.
      • Macrophages of the red Pulp remove worn-out RBC, debris, bacteria, viruses and toxins from the blood.
    • Thymus
      • Cervical nodes
      • Axillary nodes
      • Thoracic duct
      • Spleen
      • Cisterna Chyli
      • Inguinal ducts
  5. Secondary Lymphoid Areas?
    • STAPL
      • Spleen
      • Tonsils
      • Appendix
      • Peyer’s patches
      • Lymph Nodes
  6. What is the Cisterna chili?
    Enlarged terminus of the thoracic duct which drains lymph from digestive viscera.
  7. How does the composition of lymph in the Cisterna Chyli differ from that in the general lymphatic stream?
    It includes “chyli” or fatty acids from the intestines.
  8. (Q16) Know the structure of antibodies and the basics about 5 classes of them.
      • 2 heavy & constant polypeptide chains (the base) bound with 2 disulfide bonds to 2 sets of chains forming a Y, with constant sections close to the bonds and variable sections further out. In addition the outer chains are “light”, while the inner chains are “heavy”.
      • I am MAD at GE for not hiring me.
      • IgM First released during immunization. Elevated levels indicate INFECTION.
      • IgA Fights local infection; major antibody present in mucus, saliva, and tears.
      • IgD Don’t know…
      • IgG Found in Blood, Lymph, Cerebrospinal fluid (CSF): Toxin neutralization; Opsonization; Compliment, Immobilization of bacteria.
      • IgE Allergic reactions and parasitic worm infections
  9. Primary Lymphoid organs?
    • Thymus & Bone Marrow

    • (Areas where T & B-cells are created/matured.)

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