Drugs for Heart Failure
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What is the formula for CO
SV x HR
If SV decreases, the heart does what?
If HR decreases, the heard does what?
- Heart rate increases to sustain adequate CO
- Stroke volume increases
Thiazide diuretics are not effective if
- CO or GFR is low;
- if CO is low may want to use a loop diuretic
What are 2 ACE inhibitors used to treat HF?
What are two Aldosterone Antagonists
What is a major adverse effect of Aldosterone antagonists?
ARBs are used in patients that cannot tolerate ACE inhibitors and should not be used in conjunction
Beta Blockers decrease contractility of the heart, so what are they usually prescribed with
diuretic to offset negative effects
What are 2 beta blockers used to treat HF?
What are two short term treatments for HF for pts who are not responding to other treatments?
Nitroglyderine is used to.....
In HF, nitroglycerin is used to relieve acute severe pulmonary edema.
What are the adverse effects of nitroglycerine
- rebound tachycardia
Digoxin is a
- Cardiac Glycoside
- *does not decrease mortality but treats symptoms to improve quality of life
a positive inotropic effect does what?
increases the force of contraction
A negative dromotropic effect does what?
a negative chronotropic effect does what?
What is the most frequent cause of digoxin toxicity?
If the pts HR is less than __ you shouldnot administer digoxin
What stage has structural HF but no s/s
What kind of pt teaching should go on for a pt taking Digoxin?
- Never stop medication abruptly
- take you pulse before taking med
- check for swelling to legs
- monitor weight
- seek help if you have SOB or chest pain
what is the antidote for Digoxin?
- Digoxin Immune FAB iv
- charcoal given PO to prevent absorption in GI tract
What would you like to do?
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