Histo Lecture 13

Home > Flashcards > Print Preview

The flashcards below were created by user paffman7 on FreezingBlue Flashcards. What would you like to do?

  1. What is the normal range of pH in the body?
  2. What are the 3 organs that affect acid-base balance?
    • Kidneys
    • Lungs
    • Liver
  3. How do kidneys affect pH?
    • Excreting acid
    • Reabsorbing HCO3
    • Excreting NH4+
    • Creating new HCO3-
  4. How do lungs affect pH?
    Alteration in PCO2
  5. How does the liver affect pH?
    • Metabolizes NH4+ into urea (lowers pH)
    • Uses H+ in gluconeogensis (raises pH)
  6. Kidneys secrete NH4+ as a mechanism of eliminating what?
  7. Each molecule of NH4+ excreted results in formation of what?
  8. NH4+ not excreted in urine is converted into what by the liver?
  9. Acidosis stimulates what in the nephron?
    H+ secretion
  10. Chemoreceptors detect PCO2 and pH to regulate what?
    ventilatory rate
  11. Increased respiratory rate does what?
    • Decraesed PCO2
    • Increased pH
  12. What can cause metabolic acidosis?
    • Diabetic ketoacidosis
    • Diarrhea (loss of HCO3-)
    • Kidney failure (inhibition of H+ excretion)
  13. What can cause metabolic alkalosis?
    • Volume contraction (hemorrhage, loss of ECF)
    • Excessive antacid ingestion
    • Loss of acid (vomiting)
  14. What can cause respiratory acidosis? (Hypoventilation)
    • Lung Disease
    • Depressed respiratory center (sedative drugs, anaesthetics)
  15. What can cause respiratory alkalosis? (hyperventilation)
    • Drugs (caffeine, aspirin, doxapram)
    • Disorders of CNS (Stroke, meningitis)
    • High altitude
    • Anxiety, pain, fear
  16. What is normal value of HCO3?
  17. What are the three steps in assessing acid-base balance disorders in the lab?
    • Assess pH level
    • Determine metabolic v. respiratory disorder
    • Analyze compensatory response to pH change
  18. What are symptoms of metabolic acidosis?
    • Lethargy, confusion, rapid and shallow breathing
    • Shortness of breath
    • Easily fatigable, sleepiness
    • Dehydration
    • Coma in severe cases (uncontrolled diabetes mellitus)
  19. What are some symptoms of respiratory acidosis?
    • Shortness of breath
    • headache, drowsiness
    • Progression of stupor and coma
  20. What are some symptoms of alkalosis?
    • Light-headedness, syncope
    • Shortness of breath
    • Muscle twitching, muscle spasm, hand tremor
    • Numbness or tingling of face and extremities

Card Set Information

Histo Lecture 13
2011-03-14 19:46:08

Acid-Base Balance
Show Answers:

What would you like to do?

Home > Flashcards > Print Preview