RRPathCh1CellInjury.txt

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Author:
mcaster24
ID:
73466
Filename:
RRPathCh1CellInjury.txt
Updated:
2011-03-17 07:59:26
Tags:
RR Path Cell Injury
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Description:
Chapter 1 Cell Injury
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  1. What is Hypoxia?
    Inadequate oxygen to tissues
  2. Why does hypoxia kill tissue?
    • Not enough O2 downs synth of ATP.
    • 1. ATP synth occurs in inner Mito memb by oxidative phosphorylation.

    2. O2 is electron acceptor at end of ETC, and lack O2=lack ATP synth.
  3. Clinical findings of Hypoxia
    • 1. Cyanosis
    • 2. confused
    • 3. cog impairment
    • 4. lethargy
  4. Name the 5 causes of Tissue Hypoxia?
    • 1. Ischemia
    • 2. Hypoxemia
    • 3. Ventilation defect
    • 4. Perfusion defect
    • 5. Diffusion defect
  5. What is ischemia? What are the consequences? name some examples?
    decrease arterial blood flow or venous ouflow of blood.

    Examples: coronary art atherosclerosis, down CO, thrombosis of splenic vein

    Consequences 1. Atrophy 2. INfarction of tissue (necrotic) 3. organ dysfxn (heart fail)

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