Pharm-Chap 19

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  1. Preferentially stimulates muscarinic receptors, esp. GI and Bladder. (increases conctractions)
    Bethanechol (Duvoid)
  2. Tends to predominately inhibit at the NM junction- Muscarinic
    Neostigmine (Prostigmin)
  3. Name (2) drugs that may help with Alzheimer disease
    • Tacrine (Cognex)
    • Donepezil (Aricept)
  4. Name (6) clinical applications of Cholinergic Stimulants
    • Alzheimer disease
    • GI and urinary bladder atony
    • Glaucoma
    • Myasthenia Gravis
    • Reversal of neuromuscular blockage
    • reversal of anticholinergic-induced CNS toxicity
  5. What is the prototypical Antimuscarinic anticholinergic drug?
    Where does it come from?
    MOA?
    • atropine
    • from plants- belladonna and jimsonweed
    • blocks postsynaptic cholinergic muscarinic receptor
  6. Name (9) clinical applications of Antimuscarinic Drugs
    • GI system
    • PD
    • CVS
    • Motion sickness
    • Preopertative med
    • urinary tract
    • respirtatory tract
    • eye
    • cholinergic poisoning
  7. Name (5) side effects of anticholinergic drugs
    • dry mouth
    • blurred vision
    • urinary retention
    • constipation
    • tachycardia
Author
ID
73518
Card Set
Pharm-Chap 19
Description
Cholinergic Drugs
Updated
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