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What is the most prominent response to altitude?
Hyperventilation: Need to get more oxygen into the body due to low PO2
What receptors are activated at high altitudes?
Peripheral Chemoreceptors b/c the detect low PO2
What is polycythemia?
Increased RBC Production
What is the stimulus for Polycythemia?
Hypoxia (generally at high altitudes or with R-L Shunts)
What happens to 2,3-DPG at high altitudes?
Increases to release more O2 from Hb
What do diffusion defects, R-L shunts and V/Q defects do to A-a gradients?
What is the effect of supplemental O2 with R-L shunt?
No effect, b/c shunted blood is not oxygenated