pharm exame 2

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Author:
mara
ID:
73638
Filename:
pharm exame 2
Updated:
2011-03-18 01:31:03
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pharmachology
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druga
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  1. HYPOTHYROID DRUG
    ****LEVOTHYROXINE
    675-125 mcg DAY PO
  2. hypothyroid drug
    thyroid desiccate
    60-180mg day po
  3. HYPERTHYROID drug
    Prophylthiuracil
    100mg tid po maint.
  4. corticosteroids-glucacorticoids
    **HYDROCORTISONE
    IM/IV
    replacement TX (po)
    inflammation
    adrenal insufficiency
    5-30mg bid-qid po

    100-500mg IM/IV q2-10hr

    0.5-2g q2-6 **IN SHOCK
  5. corticosteroids-glucacorticoids
    Predinisone
    • inflamation
    • ashma
    • allergic
    • etc
  6. corticosteroids-glucacorticoids
    Methylprednisolone
    IM/IV sodium succinate
    • inflammation
    • immune suppression
  7. corticosteroids-glucacorticoids
    dexamethosone
    IV/IM sodium phosphate
    • inflammation
    • allergic

    IV/IM --cerebral edema (controversial)
  8. oral hypoglycemic drugs
    chloropropamide

    DM type II
    • 250-500mg
    • * elderly-- 100-125mg daily
  9. oral hypoglycemic drugs
    Glyburide
    DM type II
    1.25-10mg

    dose greater than 10mg-give bid
  10. oral hypoglycemic drugs
    Acarbose
    DM type II
    50-100mg
  11. oral hypoglycemic drugs
    ***METFORMIN

    DM type II
    • 500-800MG
    • bid
    • MAX tid po
  12. oral hypoglycemic drugs
    Sitagliptin
    DM type II
    100mg daily po
  13. anti-seizure drugs-----***PHENYTOIN DILATIN
    type of seizures:
    Tonic Clonic (Grand Mal)
    Complex Partial (psychomotor)

    *** PRINCIPAL ADV. EFFECTS?
    • CNS: nystagmus-----ataxia----slurred speech
    • gengival hyperplasia
    • folate Vit. D defficiency
    • hirsutism
  14. anti-seizure drugs-----***PHENYTOIN DILATIN
    type of seizures:Tonic Clonic (Grand Mal)Complex Partial (psychomotor)

    COMMENTS?
    • abs. depend on formulation
    • discontinue if skin rash
    • monitor blood levels to avoid adv effec
    • tiltrate dose- apply for all drugs
  15. anti-seizure drugs----- CARBAMAZEPINE tegretol
    TREAT
    TRIGEMINAL NEURAGIA
    PAIN
    BIPOLAR


    PRINCIPAL SE?
    • dizziness
    • ataxia
    • nystagmus
    • hepatic toxicity-- rare
  16. anti-seizure drugs-----PHENOBARBITOL


    ADVERSE SE?
    • SEDATION
    • DRAWSINESS
    • RARE HEP TOXICITY
    • DEF. OF FOLATE VIT D- ON PROLONGED USE
  17. anti-seizure drugs-----***PHENOBARBITOL


    COMMENTS?
    • DRUG OF CHOICE FOR NEONATAL SEIZURE
    • LONG ACTING
    • LOW RISK OF SIDE EFFECTS
  18. anti-seizure drugs-----VALPROIC ACID

    IS BROAD BUT---DONT USE FOR PETIT MAL SEIZURE

    SIDE EFFECTS?
    • N/V
    • GI --DISTRESS
    • RARE HEP TOXICITY IN KIDS LESS THAN 2
    • THROMBOCYTOPENIA

    • COMMENTS-
    • TAKE WITH FOOD
    • ALSO USED FOR COMPLEX PARTIAL SEZURE- TONIC CLONIC
    • BIPOLAR DISODER
  19. anti-seizure drugs-----GABAPENTIN
    PARTIAL SIMPLE FOCAL SEIZURE
    TREAT INTRACTABLE SEIZURE
    ADVERSE EFFEDCTS?
    • SONOLENCE
    • DIZZINESS
    • ATAXIA
    • FATIGUE
    • USE FOR
    • NEIROPHATIC PAIN
    • MIGRAINE
    • PHOPHYLAXIS
    • BIPOLAR
    • POSTHERPETIC NEURAGIA
    • DIABETIS NEUROPHATY
  20. anti-seizure drugs-----LAMOTRIGINE
    DRUG-DRUG INTERACTION-- EXEPT-gabapentin

    adverse effects?
    • dizziness
    • diplopia
    • ataxia
    • nausea
    • steven johson rash
    • rare deaths

    othe use-- bipolar
  21. anti-seizure drugs-----***DIAZEPAM-VALIUM--IV

    STATUS EPILECTICUS---drug of choice
    INJECT SLOWLY * NO FASTER THAN

    5MG/MIN

    DO NOT MIX WITH OTHER DRUGS OR DILUTE
  22. anti-seizure drugs-----***PHENYTOIN IV

    FOSPHENYTOIN IV
    INJECT SLOW NO FASTER THAN 50MG/MIN very alkaline! follow if saline injection in IV catherer

    use ONLY FOSPHENYTOIN for IM injections!

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