Pharm N301

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Author:
Anonymous
ID:
73660
Filename:
Pharm N301
Updated:
2011-03-18 06:25:47
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Pharm
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Pharm
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  1. Biguanides/Metformin
    • suppress hepatic glucose production
    • Common Adverse: nausea, diarrhea
    • Toxicity = lactic acidosis (renal and liver at risk)
    • stop 48 hours before & after IV contrast
    • only med approved for gestational
  2. Sulfonylurea
    • stimulates insulin release and reduces glucagon
    • high risk of hypo, preg X
    • Interactions: alcohol (n/v, flushing), NSAIDs (lower sugar), B blockers (block signs of hypo)
  3. Meglitinides
    • stimulates insulin release
    • adverse: hypo, pt should eat within 30 mins
  4. treatment of hyperkalemia
    • K+ restriction
    • IV calcium gluconate, regular insulin & D5W, sodium bicarb
    • removal: dialysis Kayelxelate
  5. beta blockers
    • also antiarrhythmic
    • SE: depression, impotence
    • Contraindications: chronic pulmonary conditions, sick sinus syndrome, HF
  6. alpha/beta blockers
    contraindicated in asthma, hr block, severe tachycardia, bradycardia
  7. digoxin therapeutic range
    • 0.5-0.8, infuse over at least 5 mins
    • digibind = antidote
    • yellow vision
  8. quinidine
    • antidysrhythmic
    • decreases myocardial excitability, conduction velocity and contractility
    • prevents reentry phenomenon
    • SE: embolism, GI, cinchonism, cardiotoxicity, hypotension
  9. lidocane
    • antidysrhythmic
    • suppresses automacity
    • not effective orally, never give w epi
    • excessive causes confusion and seizure, switch off as soon as stable
  10. amiodarone
    • antidysrhythmic
    • prolonged phase 3 (repolarization)
    • use in life-threatening sitch w no response to other meds
    • Preg D, many SEs also
  11. atropine
    • antidysrhythmic
    • for brady to raise hr

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