pharm exam 2 by mara

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pharm exam 2 by mara
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2011-03-18 18:59:21
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  1. WHAT IS THE PARASYMPATHETIC NEUROTRANSMITTER?
    ACETYLCHOLINE
  2. WHAT IS THE PHARMACOLOGICAL EFFECTS OF PARA?
    CHOLINERGIC
  3. WHAT IS THE FUNCTIONAL CHARACTERISTICS OF PARA?
    CONSERVATION---RESTAURATION
  4. WHAT ARE THE RECEPTORS OF SYMPA?
    ALPHA 1,2 & BETA 1,2
  5. WHAT IS THE PHARMACOLOGICAL EFFECTS OF SYMPA?
    ADRENERGETIC
  6. WHAT IS THE NEUROTRANSMITTER OF SYMPA?
    NOREPINEPHRINE
  7. WHAT ARE THE SIDE EFFECTS OF CHOLINERGICS?
    • VOMIT
    • DIAHRREA
    • REDUCES HR
    • DECREASES BP
    • SWEAT
    • SALIVATION
  8. WHAT ARE THE NAME OF THE TWO CHOLINERGIC DRUGS?
    NEO AND PILO
  9. WHAT IS THE CLINICAL USES FOR PILO?
    EYE-DROP IN OPEN ANGLE GLAUCOMA
  10. WHAT IS " NEO" CLINICAL USES?
    • ANTIDOTE- FOR CURARE*
    • STIMULATE MUSCLE TONE MG
    • ATOMIC INTESTINE AND BLADDER
  11. CHOLINERGIC STIMULARTES....?
    PARA-MIMETIC
  12. ANTI-CHOLINERGIC BLOCKS..?
    PARA--LYTIC
  13. ANTI-CHOLINERGIC PHARMALOGICAL EFFECTS?
    • RELAX MUSCLE
    • INHIBITS DUC GLANDS
    • DILATE PUPILS
    • PARALYSE ACCOMODATION MUSCLES
  14. WHYS IS ANTI-CHOL IS USES AS PRE ANESTHESIC?
    TO REDUCE SALIVATION DURING OPERATION
  15. I WHAT DISORDER ANTI-CHOLI HELPS TO REGULATE MUSCLE CONTROL?
    PARKINSON'S DISEASE.
  16. WHAT ARE THE TWO CONDITION WHERE ANTI-CHOL IS CONTRAINDICATED?
    • NARROW ANGLE GLAUCOMA
    • PROSTATIC HYPERTROPHY
  17. WHAT ARE THE NAMES OF THE TWO ANTI-CHOL DRUGS?
    • ANTROPINE
    • SCOLPO
  18. WHAT IS THE CLINICAL USE FOR SCOLPO?
    MOTION SICKNESS --PATCH
  19. WHAT IS THE CLINICAL USE FOR ANTROPINE?
    BRADYCARDIA
  20. WHAT ARE THE PRECAUTIONS OF CORTICOIDS?
    • DIABETES
    • PEPTIC ULCER
    • HYPERTENTION-= CAUSES Na RETENTION
  21. WHAT TYPE OF DM DOENST NEED INSULIN?
    TYPE II IS NIDDM
  22. WHAT IS KITOACIDOSE?
    TOO MUCH KITONES PRODUCED IN BODY DUE TO FAST METABOLISM
  23. WHAT DRUG INHIBITS INSULIN?
    • GLUCORTICOIDS
    • EPINEPRHINE
    • THYROID HORMONES
  24. GIVE 3 SYMPTOMS OF DM?
    • HYPERGLYCEMIA
    • POLYURIA
    • POLYDSYA
    • THIRSTY.. EXCESSIVE URINATION
  25. WHAT ARE THE MAIN ORGANS THAT DM DAMAGES?
    • EYES
    • KIDNEY
    • NERVES
    • VESSELS
  26. WHAT ARE THE CHARACTERISTIC OF GLARGINE LANTUS INSULIN?
    • STAY LEVELED
    • CAN'T BE MIXED
    • LONG ACTING
    • DONT HAVE ANY PICKS
  27. WHAT INSULIN COME IN SUSPENTION FORM?
    CLAUDY" LANTUS

    LONG ACTING
  28. WHAT INSULIN MUST BE DRAWN FIRST?
    • FAST ACTING, OR NPH
    • TO AVOIND CONTAMINATION WHEN MIXING WITH SLOW ACTING
  29. WHAT INSULIN IS SLOW ACTING?
    REGULAR
  30. WHAT DRUGS AFFECT INSULIN DOSAGE?
    SITAGLIPIN

    INCREASE SYNTHESIS OF INSULIN REDUCING LIVER GLUCOSE PRODUCTION
  31. WHAT IS THE INSULIN OVERDOSE ANTIDOTE?
    GLUCAGON
  32. COMPLICATION OF ISULIN OVERDOSE?
    HYPOGLYCEMIA
  33. WHAT ARE THE SIGNS OF HYPOGLYCEMIA?
    • SWEATY
    • NERVOUSNESS
    • DIZZINESS
    • WEAKNESS
  34. WHAT ARE THE ADVERSE EFF. OF SITAGLIPIN?
    • HA
    • PHARINGITIS
    • UTRI
    • HYPOGLYCEMIA
  35. WHAT ORAL DM DRUG DECREASES GLUCOSE PRODUCTION IN THE LIVER ?
    METFORMIN
  36. WHAT ARE THE DIFFERENCES IN GLYBURIDE 2ND GENERATION OF SULFONYUREA?
    • LESS DDI
    • LESS ALCOHOL SENSITIVITY
  37. WHAT ORAL DM DRUG CAUSES GI DISTRESS, VIT. DEF. AND LACTIC ACIDOSE?
    METFORMIN
  38. WHAT MD ORAL DRUG CAUSES URTI--EDEMA--HA-- WEIGHT GAIN?
    PIOGLITAZONE
  39. WHAT MD DRUG CAUSES GNS AND ANEMIA?
    ARCABOSE
  40. WHAT MD DRUG SLOWS DOWN ACTIVITY OF INCRETIN?
    SITAGLIPIN
  41. RENAL DYSFUNCTION OCCURS IF PT OVERDOSE OF WHAT MD DRUG?
    SITA
  42. WHAT MD DRUG CAN BE USED AS ADJUNCTIVE THERAPY OT TREAT TYPE I & II DM?
    PRAMLINTIDE
  43. WHAT IS THE DRU-DRUG INTERACTION OF PRAMLINTIDE?
    DO NOT MIX WITH INSULIN!
  44. WHAT ARE THE ADV. EFF'S OF PRAM?
    • HYPOGLYCEMIA
    • N/V
    • ALLERGY
    • HA
    • DIZZINESS
  45. WHAT IS THE NAME OF THE DISEASE THAT MAKE BODY PRODUCE TOO MUCH CORTISOL?
    HYPERTHYROIDISM
  46. WHAT ARE THE 3 CLASS OF HORMONES SYNTHESIZED IN ADRENAL CORTEX
    • GLUCACORTICOIDS
    • MINERALOCORTICOIDS- ALDOSTERONE
    • ANDROGENS
  47. WHAT IS THE PHARMACOLOGICAL EFFECTS OF GLUCORTICOIDS DRUGS
    • METABOLIC (FAT, CHO, PROTEIN METABOLISM)
    • ANTI-INFLAMMATORY
    • IMMUNOSUPPRESSIVE
    • SODIUM RETENTION WITH POTASSIUM LOSS
  48. WHAT IS THE PRECAUTION OF CORTICOTICOIDS IN DIABETES?
    DECREASE BLOOD SUGAR
  49. SIDE EFFECTS OD GLUCOCORTICOIDS?
    • DRUG INDUCE ==CUSHING'S SYNDROME
    • HYPERGLYCEMIA
    • MOOD CHANGES
    • OSTEOPOROSIS
    • PEPTIC ULCER
    • INCREASE SUCEPT. TO INFECTION
    • GI UPSET
  50. CLINICAL USES OF GLUCACORTICOIDS?
    • REPLACEMENT THERAPY- INSUF. PROD. OF CORTISONE
    • ANTI-INFLAMMATORY--STEROIDS
    • ALLERGIC STATES--ASHMA
    • COLLAGEN DISEASE SLE-- LUPUS, PRURITS
    • NEOPLASTIC- CANCER
    • RHEUMATIC
    • GI- ULCERATIVE COLITIS
  51. ADRENAL SUPPRESSION OCCURS WHEN?
    SUDDEN WITHDRAWAL OF STEROIDS--CAUSE ADRENAL INSUFFICIENCY
  52. WHAT CAN BE DONE TO MINIMIZE ADRENAL SUPPRESSION DURING GLUCO CORTICOID LONG TERM THERAPY?
    • ALTERNATE DAY THERAPY
    • EARLY MORNING ADMINISTRATION
  53. WHAT ARE THE DISEASE RELATED T GLUCORTICOIDES DRUGS?
    • ADRENAL INSUFFICIENCY--ADDISON'S DISEASE= NOT ENOUGH CORTISOL PRODUCTION
    • OVERPRODUCTION OF CORTISOL-- CUSHING'S DISEASE---
  54. WHAT ARE THE DRUG-DRUG INTERACTION OF GLUCORTICOIDS?
    • ORAL ANTICOAGULANTES
    • ANTIDIABETES
    • SALICYTATES-ASPIRIN
  55. HYDROCORTISONE
    • SHORT ACTING
    • LIKE NATURAL HORMONE IN ACTIVITY
    • TAKE WITH MEALS
    • LEAST POTENT
  56. PREDNISONE(ORAL)-- AND METHYLPREDINISONE (INJECTABLE)
    • INTERMEDIAN ACTING
    • MORE ANTI-INFLAMMATORY
    • LESS SODIUM RETENTION
  57. TRIAMCINOLONE (ARTISTOCORT)
    • INTERMEDIAN ACTING
    • USED IN
    • ORTHOPEDICS
    • DERMATOLOGY
    • INHALERS
  58. DEXAMETHASONE (DECADRON)
    • LONG ACTING
    • POTENT ANTIFLAMATORY
    • NO SODIUM RETENTION
    • TREAT- CEREBRAL EDEMA
  59. WHAT ARE TH MAJOR FACTOR THAT CAUSES DM?
    • VIRUSES
    • DRUG
    • GENETIC
  60. WHAT ARE THE TWO TYPES OF TYROID HORMONES?
    THYROXINE T4

    TRIIODOTHYRONINE T3
  61. CRETINISM
    • HYPOTHYROID-- CONGENITAL FORM
    • COMMON CAUSE INFLAMATION
  62. MYXEDEMA
    • HYPOTHYROID
    • LACK OF ENERGY, PUFFY FACE, WEIGHT GAIN, SENSITIVITY TO COLD, MUSCLE WEAKNESS
  63. DRUGS USED IN HYPOTHYROIDISM
    • TYROID DESSICATE
    • LEVOTHYROXINE
    • LIOTHYRONINE
  64. THYROID DESSICATE
    • ANIMAL GLAND
    • VARIABILITY IN POTENCY--MAIN PROBLEM
    • INEXPENSIVE
  65. LEVOTHYROXINE

    DRUG OF CHOICE-- ONE A DAY ONLY
    • CONVERTS TO T3 IN BODY
    • ADV. EFFECTS
    • STIMULATION OF HEART,GI
    • INSOMIA
    • WEIGHT LOSS
    • ---LONG HALF -*LIFE
  66. WHAT IS THE PREUCATION OF LEVO?
    HEART DISEASE PT'S
  67. LIOTHYRONINE

    NOT GOOD PT COMPLIANCE
    • REQUIRE MULTIPLE DOSES
    • DIFFICULT TO MONITOR LEVELS
    • MORE CARDIAC ADVERSE EFF.
    • SHORT HALF-LIFE
  68. HYPERTHYROIDISM
    EXCESS OF THYROID HORMONES ARE REALEASED
  69. WHAT TYPE OF HYPERTHYROID DISORDER CAUSES-- CARDIAC STIMULATION, WEIGHT LOSS, RESTLESSNESS, AND BULGING EYES?
    GRAVE'S DISEASE
  70. TREATMENT FOR HYPERTHYROIDISM
    PROPHYLTHIURACIL (PTU)
    • INHIBITS THE SYNTHESIS OF THYROID HORMONES- BLOCKS THYROCIADASE
    • IF WELL CONTROLLED, 6-12MONTHS-- MAY TRY TO DISCONTINUE DRUG
  71. ADVERSE EFFECTS OF PROPHYLTHIURACIL (PTU) ?
    • LOSS OF TASTE
    • N/V
    • DIZZINESS
    • LEUKOPENIA
    • AGRANULOCYTOSIS
    • __PRECAUTION IN PREGNACY-- IT CROSS BBB
  72. WHAT IS THE PREUCATION WITH DRUG-DRUG INTERACTION WIHT GRAVIS DISEASE?
    • WAFARIN- CUMADIN
    • HIGLY PROTEIN BODING
  73. WHAT HYPO DRUG HAS THE LONGEST HALF LIFE AND NOT SODIUM RETENTION?
    LEVO
  74. WHAT ARE THE 3 TREATMENTS FOR HYPERTHYROID?
    • DRUG PROPYL (PTU)
    • RADIOACTIVE IODINE
    • SURGERY

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