pharm exam 2

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Author:
cassiedh
ID:
73862
Filename:
pharm exam 2
Updated:
2011-03-19 20:19:37
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ch8
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Description:
chapter 8 objectives and review
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  1. an additional therapy given to enhance or extend the effect of the primary therapy
    adjuvant
  2. substances liberated by the body during phases of inflammation that can produce pain
    algongenic substances
  3. insensibility to pain without loss of consciousness
    analgesia
  4. agents that relieve pain by inhibitn specific pain pathways
    analgesics
  5. capable of reducing fever
    antipyretic
  6. originating or producing within the organism or one of its parts
    endogenous
  7. equal in the ability for giving pain relife
    equianalgesic
  8. a test to determine risk of bleeding
    international normalized ration (INR)
  9. reduction of circulation to an area
    ischemia
  10. an initial high dose to quickly achieve a therapeutic blood level
    loading dose
  11. sensory detection and neuronal transmission of pain stimuli
    nociception
  12. injuious or harmful
    noxious
  13. derived from opium a strong dependence producing analgesic
    opioid
  14. characterist or indicativ (diagnostic) of a particular disease or condition
    pathognomonic
  15. pain caused by the activation of pain receptors in mucocutaneous and musculoskeletal tissues
    somatic pain
  16. pain caused by the activation of pain receptors in internal organs
    visceral pain
  17. AA
    arachidonic acid
  18. APAPAPAPAPAPA
    acetaminophen
  19. ASA
    Aspirin
  20. COX
    cyclooxygenase
  21. COX 1
    cyclooxygenic inhibitors
  22. LP
    Lipoxygenase
  23. NSAIDs
    nonsteroidal anti inflammatory drugs
  24. what is the most common cause to make a pt seek dental services?
    PAIN
  25. All of the following endogenous peptides will relieve
    pain except one. Which one is the exception?
    A) Enkephalins

    B) Endorphins
    C) Dynorphins
    D) Prostaglandins
    d)prostaglandins
  26. what is the most commonly prescribed drug for orofacial pain?
    hydrocodone with APAP
  27. when do you use a narcotic versus a nonnarcotic?
    depends on the pt pain perception
  28. what is given to people with severe pain?
    cox 1 or 3 with oxycodone
  29. what is given to pt with moderate dental pain?
    cox 1 inhibitors either alone with APAP or with codeine
  30. t/f APAP can be given to a prego pt
    true
  31. t/f all cox inhibitors increase pain threshold
    true
  32. ASA, ibuprophen, naporoxen and naproxen Na are all examples of what type of inhibitors?
    cox 1
  33. where are cox 1 expressed?
    in all normal tissues
  34. t/f cox 1 increase bleeding
    true
  35. t/f cox 1 protects gastric mucosa and causes gastric irritation
    true? I dunno jackie those notes seem a little weird but it was in red so i had to put it
  36. where are cox 2 expressed?
    primarily in brain, kidneys and female reproduction system and bone
  37. what is the action of cox 2 inhibitors?
    raise pain threshold
  38. cox 2 inhibitors block endothelial prostacycline synthesis to cause? 2
    • blood clots
    • vasoconstriction
  39. where are cox 3 expressed?
    CNS
  40. what is an example of cox 3
    APAP (tylenol)
  41. what is an example of cox 2 inhibitor?
    celebrex
  42. t/f cox 3 has no anti inflammatory effect
    true
  43. t/f cox 3 has analgesic and antipyretic effect
    true inhibt prostaglandin in CNS
  44. t/f APAP has effect on the platelet function
    FALSE NO NO NO effect on platelet function. blah blah blah I am so sick of pharm!
  45. with 500mg of aspirin what happens to bleeding times?
    prolongs bleeding times (8 days)
  46. what is the prototype of penicillin?
    penicillin G
  47. what antibiotic is prone to resistance (immunity common)?
    erythromycin
  48. when do you give premed? 7
    • cardiac conditions
    • aritificial heart valves
    • specific congenital heart defects
    • unrepaired or incompletely repaired cyanotic congenital heart disease (shunts and conduits)
    • completely repaired congenital hear defect with prosthetic material or device during the 1st 6 moths of post surgery
    • repaired congenital heart defect with residual defect at site or adjacent to site of prostheic patch or device
    • cardiac transplant that develops valvuar problems
  49. you give premed for a cardiac transplant that has no problems
    no only if vavlular problems
  50. t/f premed is needed for cardiac conditions
    true
  51. t/f no pre med is needed for artificial heart valves
    false premed needed
  52. what interacts with antibiotics? 3
    • oral contraceptives
    • rifampin (for TB)
    • pseudomembranous colitis
  53. if stool appears black while taking antibiotics what should you do?
    STOP antibiotics
  54. with what antibiotics do you develop pseudomembranous colitis?
    clindamycin and lincomycin

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