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jdonaldson
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To which class of drugs does cilostazol belong?
Antiplatelet agents - PDE type III inhibitor
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What indications are associated with cilostazol?
- Peripheral vascular disease.
- Intermittent claudication (Raynauld's syndrome).
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What helps the absorption of cilostazol?
Administration with a high fat meal.
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True or false?
Cilostazol is metabolized to its active form.
True.
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What is cilostazol's target MOA?
Competitive inhibition of PDE 3, increasing platelet cAMP and thus inhibiting platelet aggregation.
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As per cilostazol's MOA, what effects are experienced by the body?
- Inhibited platelet aggregation.
- Vasodilation.
- Antiproliferative for vascular smooth muscle?
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What is an adverse event associated with cilostazol?
HA (27-34%).
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Increased levels of platelet cAMP would normally cause...
Not aggregate.
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