Cilostazol

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  1. To which class of drugs does cilostazol belong?
    Antiplatelet agents - PDE type III inhibitor
  2. What indications are associated with cilostazol?
    • Peripheral vascular disease.
    • Intermittent claudication (Raynauld's syndrome).
  3. What helps the absorption of cilostazol?
    Administration with a high fat meal.
  4. True or false?

    Cilostazol is metabolized to its active form.
    True.
  5. What is cilostazol's target MOA?
    Competitive inhibition of PDE 3, increasing platelet cAMP and thus inhibiting platelet aggregation.
  6. As per cilostazol's MOA, what effects are experienced by the body?
    • Inhibited platelet aggregation.
    • Vasodilation.
    • Antiproliferative for vascular smooth muscle?
  7. What is an adverse event associated with cilostazol?
    HA (27-34%).
  8. Increased levels of platelet cAMP would normally cause...
    Not aggregate.

Card Set Information

Author:
 jdonaldson
ID:
 74246
Filename:
 Cilostazol
Updated:
 2011-03-21 20:31:46
Tags:
james James donaldson Donaldson usp USP
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Description:
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