phys #13.txt

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  1. What polysaccharide is the gold standard used to measure GFR?
    Inulin
  2. What is normal creatine clearance?
    80-110 ml
  3. What 4 items are required for the Cockcroft-gault equation?
    • 1) Age
    • 2) Weight
    • 3) Sex
    • 4) Pcr
  4. What 4 items are required for the MDRD-4 equation?
    • 1) Age
    • 2) Sex
    • 3) Ethnicity
    • 4) Pcr
  5. What is normal Blood urea nitrogen levels (BUN)?
    9-18 mg/ml
  6. How much urea is reabsorbed in a normal patient?
    1/2
  7. As GFR decreases, how does that affect Urea reabsorption?
    Urea reabsorption increases
  8. What is the normal BUN:Cr ratio?
    10-15
  9. What is the BUN:Cr ration if a patient persists with 1) Acute tubular necrosis and 2) Nephron loss?
    Normal
  10. What is the BUN:Cr ratio in a patient with 1) Dehydration 2) Blood Loss and 3) obstruction?
    • High
    • ***due to low GFR which causes more reabsorption of urea
  11. What is the BUN:Cr ratio in a patient with 1) Skeletal muscle breakdown 2) Liver disease and 3) malnutrition and why?
    • Low
    • ** Skeletal breakdown = high Cr
    • ** Liver disease and malnutrition = low Urea
  12. What is normal Cr clearance for 1) males and 2) Females?
    • 1) Males: 97-140
    • 2) Females: 85-125
  13. What type of substance is either less than Ccr (Creatine clearance) or more than Ccr?
    • Less = reabsorbed
    • More = Secreted
  14. How much glucose is reabsorbed in the kidney?
    All of it (0 is secreted)
  15. What does Cx/Cinulin = 1.0 mean?
    GFR marker, neither secreted or reabsorbed, but it is filtered completely
  16. What does Cx/Cinulin < 1.0 mean?
    either not filtered or filtered and reabsorbed
  17. What does Cx/Cinulin > 1.0 mean?
    Filtered and secreted
  18. Why is PAH important?
    Some is filtered and the rest is secreted out of plasma
  19. What is PAH a measure of?
    RPF since it is secreted out of the plasma
  20. What percentage of RPF reaches the nephrons?
    90%
  21. What is the normal Plasma PAH?
    1 mg/ml

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Author:
kepling
ID:
74494
Filename:
phys #13.txt
Updated:
2011-04-04 23:41:05
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phys
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phys #13
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