Antivirals

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Author:
Samilou
ID:
74554
Filename:
Antivirals
Updated:
2011-03-22 18:37:34
Tags:
Antibiotics Antivirals Test
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Description:
Ch 40
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  1. 6 Viruses killed by current antiviral therapy
    • cytomegalovirus (CMV)
    • Hepatitis
    • HSV
    • HIV
    • Influenza
    • Respiratory syncytial virus (RSV)
  2. What is a virion?
    mature virus particle
  3. The inner core of the virion, composed of DNA or RNA.
    genome
  4. 4 Routes a virus can enter a host
    • inhalation
    • ingestion
    • transplacentally
    • innoculations
  5. Used to treat infections caused by viruses other than HIV.
    Antivirals
  6. Used to treat infections caused by HIV
    antiretroviral
  7. Concentrated antibodies that can attack and destroy viruses.
    Immunoglobulin
  8. 6 Steps of Virus replication
    • 1-Attachment to host
    • 2-Uncoating of virus, and entry of viral nucleic acid into host cell
    • 3-Control of RNA, DNA, and/or protein production
    • 4-Production of viral subunits
    • 5-Assembly of virions
    • 6- Release of virions
  9. Symmetrel is the TN of _______
    amantadine
  10. Flumadine is the TN of _______
    rimantadine
  11. What does amantadine and rimantadine treat?
    Influenza A
  12. Foscavir is the TN of _______
    foscarnet
  13. What is fascarnet used to treat?
    (2)
    • CMV
    • HSV
  14. Tamiflu is the TN of ________
    oseltamivir
  15. Relenza is the TN of ________
    zanamivir
  16. oseltamivir and zanamivir are used to treat what?
    Influenza A and B
  17. Zovirax is the TN of ________
    acyclovir
  18. What antiviral is used to treat HSV 1,2, and 3
    acyclovir
  19. Cytovene is the TN of __________
    ganciclovir
  20. What do you use ganciclovir to treat?
    CMV infections
  21. Copegus is the TN of ________
    ribavirin
  22. What drug treats lower respiratory RSV infections in infants?
    ribavirin
  23. Name 3 ways retroviruses are transmitted.
    • sexual activity
    • intravenous drug use
    • perinatally from mom to child
  24. Name the 4 stages of the HIV infection
    • 1-Asymptomatic
    • 2-General symptoms
    • 3-Moderate symptoms
    • 4-Severe symptoms
  25. List characteristics of Stage 1 HIV infection.
    • swollen lymph nodes
    • CD4 count remains in normal limits
  26. List characterstics of Stage 2 HIV infection.
    • Symptoms like fever, rash, night sweats, diarrhea, and shingles start to appear
    • Occurs 3 weeks to 3 months after exposure
    • CD4 count begins to drop
  27. List characteristics of Stage 3 HIV
    • Weight loss, chronic diarrhea and fever continue
    • Opportunistic infections begin to occur
  28. What is currently the leading cause of death worldwide for HIV-infected patients?
    Pulmonary TB
  29. List the types of Opportunistic Infections
    (5)
    • Protozoal
    • Fungal
    • Bacterial
    • Viral
    • Opportunistic neoplasias
  30. What does HAART stand for and what is it?
    • Highly active antiretroviral therapy
    • Combines various agents (cocktails) to prevent viral overload inhibiting cell replication within various stages

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