528.3 LECTURE 1

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VASUpharm14
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74624
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528.3 LECTURE 1
Updated:
2011-03-22 22:14:23
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module 2 exam 3
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  1. 4 titles of system regarding kidneys
    • 1. renal system
    • 2. kidney system
    • 3. nephron system
    • 4. urinary system
    • *Naming system based on what is excreted
  2. 10 functions of kidneys
    • 1. BV regulation
    • 2. BP regulation
    • 3. Salt/ion regulation
    • 4. Nutrient conservation
    • 5. pH regulation
    • 6. waste removal
    • 7. RBC production
    • 8. Creates vitamin D
    • 9. Regulates calcium
    • 10. Detoxification
  3. 4 urine components in the renal system
    • 1. wet
    • 2. stinks
    • 3. yellow
    • 4. salty
  4. context: 4 urine components - wet
    water input
    50/50 water and food
  5. context: 4 urine components - wet
    water output
    • 50% urine (regulate BV)
    • 25% sweat (regulate temperature)
    • 20% vapor (regulate gas exchange)
    • 5% feces (regulate consistency)
  6. context: 4 urine components - stinks
    molecular composition (4 things taken in)
    • 1. lipids
    • 2. carbohydrates
    • 3. proteins
    • 4. purines/pyrimidines
  7. context: 4 urine components - stinks
    molecular decomposition
    • H and O excrete - as water in sweat, feces, vapor, and urine
    • C excrete - via breathing
    • N excrete - urinate out
  8. context: 4 urine components - stinks
    3 Nitrogenous wastes = stinky
    • 1. ammonia - fish
    • 2. urea - we produce this most
    • 3. uric acid - complex and too much effort to make/birds worry about compactness and will make this
  9. context: 4 urine components - yellow
    process to get yellow
    • *waste regulation
    • (1) RBC --> (2) Hemoglobin --> (3) Bilirubin --> (4) Urobilin (yellow) --> excreted in urine
  10. context: 4 urine components - salty
    salt regulation
    • *to get rid of excess and excrete less if not much
    • sodium chloride
  11. blood route
    (1) heart --> (2) descending aorta --> (3) renal artery --> (4) KIDNEY (important to filter the blood) --> (5) renal vein --> (6) inferior vena cava --> (7) heart
  12. context: volumes
    blood into kidneys
    ~1500 L a day (~25% of C.O.)
  13. context: volumes
    urine out of kidneys
    • ~1.2 L a day (~3 cans of soda)
    • *only filter a small amount
  14. urine route
    (1) KIDNEY --> (2) ureter --> (3) bladder (for storage)--> (4) urethra
  15. nephron
    • function unit of kidneys
    • -made of a whole bunch of cells, not just one cell
    • *1.25 million nephrons per kidney
    • *surrounded by capillaries for a lot of exchange (not just at glomerulus)
  16. 3 parts in anatomy of nephron
    • 1. Corpuscle
    • 2. Tubule
    • 3. Ducts
  17. context: 3 parts in anatomy of nephron
    corpuscle
    • 1. glomerulus: blood vessels
    • 2. Bowman's Capsule: surrounds glomerulus (connective tissue)
  18. context: 3 parts in anatomy of nephron
    tubule
    • 1. proximal convoluted tubule (PCT)
    • 2. Loop of Henle (LOH) : descending, ascending, thick, thin
    • 3. Distal convoluted tubule (DCT)
  19. context: 3 parts in anatomy of nephron
    ducts
    • 1. collecting ducts: shared CDs (other nephrons feed into the CDs)
    • 2. Papillary ducts: distal ducts --> to the ureter (to bladder)
  20. context: physiology of 3 parts of nephron
    corpuscle (G, BC)
    • 1. filter blood
    • 2. water, ions, and small molecules pass through fenestrated capillaries into tubules
  21. context: physiology of 3 parts of nephron
    tubule (PCT, LOH, DCT)
    • 1. reabsorb needed water, ions, and small molecules back into blood
    • 2. secrete unneeded water, ions, small molecules into tubules from blood
  22. context: physiology of 3 parts of nephron
    ducts (collecting, papillary)
    • collecting ducts:
    • 1. reabsorption
    • 2. secretion
    • papillary ducts:
    • 1. excretion of unwanted water, ions, small molecules --> out as urine

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