Substance Abuse Meds

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What types of drugs help treat alcoholism?
- Disulfiram (Antabuse)
- Naltrexone (ReVia)
- Acamprosate (Campral)
- Fluoxetine
Disulfiram (Antabuse):

Goal:
S/S:
Develop fear of reaction
- N/V
- Tachycardia
Naltrexone (ReVia):

Action:
S/S:
- Opiate antagonist
- (Decreases pleasure with drinking and opitate use too)
- Nausea
- GI Distress
- Headache
(Start on low dose of 25mg and work up to therapeutic dose of 50mg)
What types of drugs help treat Opiate abuse?
- Naltrexone (ReVia)
- Methadone
- Buprenorphine (Subutex or Suboxone)
(Decrease relapse rates)
Methadone:

Action:
Benefit:
Risks:
S/S:
Blocks pleasure receptors
- Decrease relapse rates, IV drug use, mortality
- Increase social and occupational function
- Increase QT interval
- Patient will use heroin as well
- Respiratory depression
- Constipation
- Difficult withdrawal
- 3 year treatment
Buprenorphine (Subutex or Suboxone):

Action:

Opiate agonist

Decrease cravings but not as effective as methadone