Picornaviridae

Card Set Information

Author:
p.reilly1227
ID:
75001
Filename:
Picornaviridae
Updated:
2011-03-24 15:17:03
Tags:
Virology Picornaviridae
Folders:

Description:
Virology, Picornaviridae
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  1. Picornaviridae's virion is ___________.
    naked icosahedron
  2. Picornaviridae's genome is ___________.
    Linear (+) ssRNA
  3. Picornaviridae's genome features _____________.
    5' NTR with IRES, VPg, and a poly A tail
  4. Picornaviridae's genes are translated___________.
    Ttranslated as 1 polyprotein that is autocatalytically cleaved by viral proteinases.
  5. Autocatalytic cleavage works by _________, which is why________?
    As picornaviridae's genome is translated, the secondary structure folds and forms a proteinase while still part of the polyprotein. This section of the protein cleaves itself and acts as a proteinase for other regions which frees up other proteinases and individual proteins. For this reason a complete full-length polyproteins are rarely found.
  6. Examples of diseases caused by Picornaviridae include ________.
    • Rhino
    • Poilio
    • Meningitis
    • Hepatitis A
    • Myocarditis
  7. Picornaviridae's distinct characteristics include _______, __________, ___________.
    • Translation begins at IRES
    • Autoproteolytic cleavage
    • RNA replication is associated with vesicles in the cytoplasm.

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