Card Set Information
Flaviviridae's virion is ___________.
Icosahedral and enveloped
Flaviviridae's envelope is characterised by ____________.
Glycoproteins with icosahedral symmetry
Flaviviridae's genome is _________.
Linear (+) ssRNA
Flaviviridae's genome features _______.
a 5' cap an
poly A tail.
Flaviviridae's genes are translated ___________ and ____________.
as 1 polyprotein that is that is processed by viral and cellular proteinases
NS2/3 is_________ to create ______ which is a ______.
A nonstructural autoprotease
cleaves at the NS2/3
junction to make
which is a
for polyprotein processing and RNA rep
Diseases caused by Flavi include _______...
Flaviviridae's distinct characteristics include ______, ________, __________, ________.
Vector transmission (not hep C)
Major envelope protein (E1/2) is parallel to lipid membrane
Pesti and Hepaci have IRES
Virions assemble by budding at the ER and are released by exocytosis