MCB Exam 3-D

Card Set Information

Author:
bkheath
ID:
75935
Filename:
MCB Exam 3-D
Updated:
2011-03-29 17:35:33
Tags:
Microbial Diseases Respiratory System
Folders:

Description:
Microbial Diseases of Respiratory Tract System
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user bkheath on FreezingBlue Flashcards. What would you like to do?


  1. Ex of normal microbiota of upper resp tract that are also opportunitistic pathogens (3)
    • Haemophilis influenzae: can colonize the nose
    • Staphyloccous aureus: normal microbiota in some ppl
    • Diptheroids: can colonize the nose & nasal cavity
  2. Streptococcal Respiratory Diseases
    aka strep throat

    What org causes it
    VF
    How get it
    S&S
    • Group A streptococci (S. pyogenes) (SPY)- a flesh eating bacteria
    • VF: M proteins (antiphagocytic), hyaluronic acid, capsule, streptokinases, C5a peptidase, pyrogenic toxins, streptlysins
    • Enter by person inhaling droplets
    • S&S: sore throat, diff to swallow, may become scarlet or rheumatic fever
  3. VF of S. pyogenes
    • M proteins- antiphagocytic
    • Hyaluronic acid
    • Capsule
    • Streptokinases
    • C5a peptidase
    • Pyrogenic toxins
    • Streptlysins- toxins it produces which kill red & white blood cells & platelets
  4. Diphtheria organism is ________ _________
    Describe it
    • Cornybacterium diptheriae
    • G+ bacterium
    • Facultative anaerobe
  5. Diptheria
    How & who gets it:
    VF:
    S&S:
    Trtmt:
    Vaccine:
    • Enters via resp droplets or skin contact
    • Susceptibility- Immunocompromised ppl
    • VF: its toxin prevents polypep synthesis & causes cell death
    • S&S: sore throat, oozing greyish fluid that hardens into pseudomembrane that can obstruct airrways; "bull throat"
    • Trtmt: give antitoxin & antibiotic
    • Immunization: DPT trio
  6. DPT immunization:
    • Diptheria
    • Pertussis (whooping cough)
    • Tetanus
  7. Common cold
    What org causes it
    How get it
    Where infection is
    S&S
    • Rhinoviruses most common, but many others
    • Enter via coughing/sneezing, fomites (inanimate object carring virus)
    • Infects upper resp system
    • S&S: sneezing, running nose, congestion, sore throat, malaise, cough; but NO fever
  8. Ex bacterial infections of lower resp system
    • Bacterial pneumonia
    • Legionnaire's disease
    • Pertussis (whooping cough)
    • Tuberculosis
  9. 5 Types Pneumonia
    • Can be categorized by type of org causing or affected region:
    • 1. Bacterial pneumonia- most serious & most common
    • 2. Pneumonococcal pneumonia
    • 3. Mycoplasmal Pneumonia (Primary Atypical Pneumonia)- caused by Mycobacterium
    • 4. Lobar pneumonia- involves entire lobes of lungs
    • 5. Nosocomial pneumonia- from hospital
  10. Pneumonia
    Inflammation of lungs w/fluid filled alveoli & bronchioles
  11. Pneumococcal Pneumonia
    What org causes
    How & who gets it
    VF
    Incubation
    S&S
    Trtmt
    • Streptococcus pneumoniae
    • Enters via inhalation
    • Immunocompromised ppl- very common AIDS ppl
    • VF: Adhesions, capsule, pneumolysin
    • Incubation: 1-3 dys
    • S&S: fever, chills, congestion, cough, chest pain, short rapid breathing
    • Trtmt: Penicillin
  12. Primary Atypical (Mycoplasmal) Pneumonia
    Mycoplasma pneumoniae

    How & who gets it
    Incubation
    VF
    S&S
    Trmt
    • Enters via nasal secretions of ppl close contact
    • Susceptibility: HS & college students
    • VF: adhesion protein
    • Incubation: 1-4 wks
    • S&S: may have none; fever, malaise, sore throat, excessive sweating
    • Trmt: Tetracycline, erythromycin
  13. Legionellosis (Legionnaire's Disease)
    Legionella pneumophila

    How & who gets it
    S&S
    Diagnoses
    Trtmt
    Prevention
    • Enters via inhale vesicles that are filled w/it; associated w/cooling towers
    • Susceptibility: elderly, smokers, immonocomp ppl
    • S&S: typical pneumonia symptoms; maybe complications of GI tract, CNS, liver, & kidneys
    • Diagnosis: org's presence or antibodies made
    • Trtmt: erythromycin
    • Prevention: reduce it's presence in water
  14. TB
    (Mycobacterium tuberculosis)

    Susceptibility:
    VF:
    S&S:
    Diagnosis:
    • Susceptibility: immonocomp ppl, leading killer in HIV+ ppl
    • VF: mycolic acid in cell wall; cord factor (surface glycolipid which resists phagocytosis) for it to cause disease
    • S&S: initally minor cough/fever; later diff breathing, chest pain, wheezing, coughing blood
    • Diagnosis: skin test but doesn't tell if person was simply exposed or vaccinated
  15. Inhalation Anthrax
    Bacillus anthracis

    How get it
    VF
    S&S
    Diagnosis
    Prevention
    • Inhalation of endospores
    • VF: capsule, toxin
    • S&S: initial cold/flu-like, progresses to severe coughing, diff breathing, shock, death
    • Diagnosis: bacteria in sputum (spit w/phlegm)
    • Prevention: vaccine for military, health care workers
  16. Influenza-Types A & B- 2 strains are:
    Hemagglutinin antigen (HA) and neuraminidase antigen (NA) strains which mutate often
  17. Antigenic drift & antigenic shift mutations of influenza virus
    8 RNA pieces of virus are rearranged & recombined w/each other to make new combinations
  18. 2 Ex of fungal infections of Lower Resp System
    Histoplasmosis, Pneumocystis pneumonia
  19. Histoplasmosis
    Histoplasmosis capsulatum

    Abt it:
    How get it
    Epidemiology
    Trmt
    • Most common fungal systemic disease
    • Soil---> human; children
    • Eastern US & parts of Africa, Central/S America
    • Trmt: Amphotericin B
  20. Pneumocystis Pneumonia (PCP)
    Pneumocystis jiroveci (prev P. carinii)

    How & who gets it
    • Inhale droplets containing the fungus
    • Immnocomp, esp AIDS ppl

What would you like to do?

Home > Flashcards > Print Preview