Home > Preview
The flashcards below were created by user
on FreezingBlue Flashcards.
Mechanism of action
Synthetic corticosteroid that suppresses acute and chronic inflammation; potentiates vascular smooth muscle relaxation by beta-adrenergic agonists.
Acute spinal cord trauma, anaphylaxis, bronchodilator for unreponsive asthma.
Premature infants, systemic fungal infections, use with caution in pts. with gastrointestinal bleeding.
Headache, hypertension, sodium and water retention, CHF, Hypokalemia, alkalosis, peptic ulcer disease, nausea, vomiting.
Hypoglycemic responses to insulin and hypoglycemic agents may be blunted. Potassium-depleting agents may exacerbate hypokalemia effects.
40, 125, 500, and 1,000 mg vials
Dosage and Administration
- Adult: acute spinal cord injury-30 mg/kg IV over 30 minutes followed by infusion: 5.4 mg/kg/h. Asthma, COPD: 1-2 mg/kg IV.
- Pediatric: acute spinal cord trauma: 30 mg/kg IV over 30 minutes; infusion: 5.4 mg/kg/h. Asthma: 1-2 mg/kg/dose IV.
Duration of action
- Onset of action: 1-2 hours.
- Peak effects: variable
- Duration of action: 8-24 hours
Pregnancy safety: not established. Not effective if spinal cord injury greater than 8 hours. Crosses the placenta and may cause fetal harm.
What would you like to do?
Home > Flashcards > Print Preview