N 304 Neuro Drugs

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Author:
dlourey
ID:
76139
Filename:
N 304 Neuro Drugs
Updated:
2011-03-30 01:19:34
Tags:
Neuro Drugs
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Description:
N 304 Neuro Drugs
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  1. Anticonvulsant therapy
    • Stabilize cell membranes
    • Effects
    • - increased motor cortex threshold
    • -reduces spread of discharge
    • -decreases nerve conduction
  2. What are the anticonvulsants Drug classes?
    • Hydantoins
    • Barbiturates
    • Succinimides
    • Diones
    • Benzodiazepines
    • Misc.
  3. Anticonvulsants peds & geri considerations
    • peds: skin rash, gingival hyperplasia, cognitive
    • geri: skin rash, metabolize slowly
  4. Hydantions: Action & SE
    • Action: inhibit spread of seizure
    • SE:
    • - lethargy
    • -abnormal movements
    • -cognitive changes
    • -gingival hyperplasia
    • -acne
    • -peripheral polyneuropathy
    • -bone marrow suppression
    • -skin rashes
  5. Drugs in HYDANTIONS group
    • The "toin" group
    • Phenytoin (Dilantin)
    • Mephenytoin (Mesantoin)
    • Fosphenytoin (Cerebyx)
    • Ethotoin (Peganone)
  6. Barbiturates: Action & SE
    • Action: Depress CNS
    • SE:
    • -Sedation
    • -Depression
    • -Sleep disorders
    • -Cognitive
    • -Kids = irritable & hyperactive
  7. Barbiturates Drugs
    • The "barbital" group
    • Phenobarbital
    • Amobarbital (amytal)
    • Mephobarbital (Mebaral)
  8. Succinimides Action & SE
    • Actions: increase seizure threshold & decrease nerve impulses
    • SE:
    • -Drowsiness
    • -Agranulocytosis
    • -Thrombocytopenia
    • -SLE
    • -N/A
    • -Take with food
  9. Drugs in the SUCCINIMIDES group
    • the "suximide" group
    • - Ethosuximide (Zarontin)
    • -Methsuximide (Celontin)
    • -Phensuximide (Milontin)
  10. Benzodiazepine Action & SE
    • Action: Supress seizure activity, increases effects of GABA, also used for anxiety
    • SE
    • -drowsiness
    • -ataxia
    • -presonailty changes
    • -hiccups
    • -loss of decterity
    • -dry mouth
    • -N/V
    • -HA
  11. Benzodiazepine drugs in this group
    • Clonazepam (Klonopin)
    • Diazepam (Valium)
    • Clorazepate (Tranxene)
    • Lorazepam ( Ativan)

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