Virology Paramoxyviruses and Rhabdoviruses

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p.reilly1227
ID:
76250
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Virology Paramoxyviruses and Rhabdoviruses
Updated:
2011-03-30 16:37:03
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Virology Paramoxyviruses Rhabdoviruses
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Virology Paramoxyviruses and Rhabdoviruses
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  1. Paramoxyviruses and Rhabdoviruses are part of the ________ group, which is _________.
    • Mononegaviruses
    • a group of negative stranded RNA viruses that share common genome structure and replication mechanism
  2. Fundamental characteristics of viruses in the Mononegavirus group include ______, ________, ______, and ______.
    • 1) Genome is single RNA molecule packaged in a helical nucleocapsid
    • 2) Nucleocapsids are enclosed by env derived from plasma membrane
    • 3) A viruses coded RNA pol packaged in the virion syn viral mRNAs
    • 4) Pol begins trx at 3' end and sequentially trx 5-10 genes, terminating and releasing each mRNA before beggining a new one
  3. Paramoxyviruses and Rhabdoviruses virion is ________.
    • Common
    • Coiled helical nucleocapsid with env derived from plasma membrane.
    • Individual
    • Paramyxo - spherical and filamentous
    • Rhabdo - rod shaped
  4. Paramoxyviruses and Rhabdoviruses genome is __________.
    linear (-) ssRNA with 1 segment
  5. Paramoxyviruses and Rhabdoviruses genes are ___________ and ___________.
    trx sequentially from 3' to 5' by viral RNA pol. Each genes gives one mRNA.
  6. Paramoxyviruses and Rhabdoviruses proteins __________.
    come packaged in the virion
  7. Paramoxyviruses and Rhabdoviruses distinctive characteristics include _______, ___________, _________, and ________.
    • RdRp in virion trx genome into mRNAs
    • One trx promoter at 3' end - start stop mechanism
    • Full length genome and antigenome RNA is always present as assembled nucleocapsids
    • Some paramoxy cause syncytia
  8. Paramoxyviruses and Rhabdoviruses diseases include ________.
    • Paramoxy - measles mumps, parainfluenza
    • Rhabdo - rabies (in humans) and vesicular stomatitis virus (cattle)

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