Card Set Information
glaucoma meds blk4
carbonic anhydrase inhibitor
prophylaxis/treatment of altitude sickness, glaucoma
reduction of intraocular pressure, reduction in aqueous humor production
brimonidine (apraclonidine, clonidine)
alpha2 adregneric agonist
open-angle glaucoma, ocular HTN
reduces aqueous humor production and uveoscleral outflow w/o mydriasis
: xerostomia (dry mouth), blurred vision, occular irritation
carbonic anhydrase inhibitor (CA-II)
: selective control of aqueous humor production and IOP
F2alpha prostagladin agonist
treats elevated IOP
increased uveoscleral outflow
: increases amount of brown pigment, burning/stinging, blurred vision
parenteral osmotic diuretic, emergency reduction in IOP
: pulmonary congestion, fluid/electrolyte imbalance, acidosis, dry mouth, urinary retention, edema
nonselective beta-adrenergic antagonist
reduces aqueous humor production by preventing Na+ from entering into aqueous humor
Sympathetic innervation of eye
via superior cervical ganglion/internal carotid
via oculomotor nerve/ciliary ganglion
What effect will an alpha1 agonist have on the eye?
(no loss of accomodation/cycloplegia)
What effect will a muscarinic antagonist have on the eye?
blocks contraction of ciliary body, preventing accomodation
blocks contraction of the sphincter pupillae, causing mydriasis
therefore, if loss of accomodation, mydriasis must be present!
obstruction of aqueous drainage
incr. of intraocular pressure can damage the optic nerve
"cup" becomes larger
only treatment of this is reduction of IOP
What classes of drugs increase aqueous humor outflow?
parasympathomimetics (trabecular network)
prostagladin agonists (uveoscleral outflow)
What classes of drugs decrease aqueous humor secretion?
alpha2 adrenergic agonists
carbonic anhydrase inhibitors
What is the "angle"?
between iris and cornea