Treatment of TB rarely requires in-hospital care.
The mainstay of TB treatment is pharmacological.
Drug therapy is used to treat individuals with disease as well as prevent disease in infected persons.
Drugs are usually administered as a single dose before breakfast to ensure adequate absorption.
For active disease, treatment consists of at least 4 drugs to start
5 primary drugs are: INH, Rifampin, PZA, Ethambutol, Streptomycin
In most areas of the United States, drug therapy is free of charge.
- Greater than 90% of clients convert to negative sputum status within 3 months. Take with food No alcohol
- INH is bacteriosideal, it can cause peripheral neurides: numbness and tingling (People are on B6 vitamins also)
Rfampin is bacteriosidal broad spectrum (urine and tear turn orange) it decreases effectiveness of oral contraceptive and anticoagulants. (These are the drugs pt stay on INH AND RFAMPIN they cause liver problems)
- PZA cause jaundice,
- Ethambutol: need vision test ( only on it for a couple of month)
- Streptomycin: causes audio toxity
- Important to follow up to ensure adherence to treatment regimen.
The major side-effect of INH, Rifampin, and PZA is hepatitis