DES: potent analgesic & sedative that causes some vasodilation, reducing venus return & reduced myocardial O2 demand.
IND: moderate to severe pain & in MI & to reduce renous return in pulmonary edema.
CI: hypersensitivity to opiates, undiagnosed head or abdominal injury, hypotension, or volume depletion, acute asthma, COPD, severe respiratory depression or pulmonary edema due to chemical inhalation.
PC: elderly, children or debilitated patients. naloxone should be readily available to counteract the effects of morphine.
DOSE: Pain: 2.5-15 mg IV; 5-20 mg IM/SQ. Ped: 0.05-0.1 mg/kg IV; 0.1-0.2 mg/kg IM/SQ AMI or PE: 1-2 mg (6-10 min response)
NAME/CLASS: narcan/narcotic antagonist
DES: naloxone is a pure narcotic antagonist that blocks the effects of both natural & synthetic narcotics and may reverse respiratory depression.
IND: narcotic and synthetic narcotic overdose, coma of unknown origin.
CI: hypersensitivitiy to the drug, non-narcotic-induced respiratory depression.
PC: possible dependency (including newborns). 1/2 life shorter than than most narcotics (pt may return to overdose state)
DOSE: 0.4-2.0 mg IV/IM/IN (ET 2-2.5X the dose). repeated/ 2-3 min as needed up to 10 mg. Ped: 0.01 mg IV/IM (ET 2-2.5X the dose) repeated/ 2-3 min as needed up to 10 mg.
DES: selective blocking agent of the serotonin receptor type
IND: prevention of nausea & intractible vomiting
PC: may mask a progressive ileus &/or gastric distension