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Dextrose 50% (D50)
Trade Name
Dextrose
D50
D50W
Glucose
Dextrose 50% (D50)
Class
Carbohydrate
Hypertonic Solution
Dextrose 50% (D50)
Mechanism of Action
Rapidly increases serum glucose levels.
Short-term osmotic diuresis
Dextrose 50% (D50)
Indications
Hypoglycemia
Altered Level of Consciousness
Coma of Unknown Etiology
Seizure of Unknown Etiology
Status Epilepticus (controversial)
Dextrose 50% (D50)
Contraindications
Intracranial Hemorrhage
Delirium Tremens
Ineffective Without Thiamine (?)
Dextrose 50% (D50)
Adverse Reactions
Extravasation leads to tissue necrosis
Warmth
Pain
Burning
Thrombophlebitis
Rhabdomyositis (rare form of cardiomyopathy)
Dextrose 50% (D50)
Drug Interactions
Sodium bicarbonate
Coumadin
Dextrose 50% (D50)
How Supplied
25 gm/ 50 ml pre-filled syringes (500 mg/ml)
Dextrose 50% (D50)
Dosage and Administration
Adult
12.5-25 gram slow IV; may be repeated as necessary
Dextrose 50% (D50)
Dosage and Administration
Pediatric
0.5-1 gm/kg/dose slow IV; may be repeated as necessary
D10%
: 0.5 gm/kg IV Bolus (for neonates)
D25%
: 0.5 gm/kg IV Bolus (if estimated body weight < 50kg)
D50%
: 0.5 gm/kg IV Bolus (if estimated body weight> 50 kg)
Dextrose 50% (D50)
Duration of Action
Onset
: less than 1 minute
Peak effects
: Variable
Duration
: Variable
Dextrose 50% (D50)
Special Considerations
Administer thiamine prior to D50 in known alcoholic patients
Draw blood sugar before administering
Do not administer to patients with known CVA unless hypoglycemia documented
Author
papeirce
ID
76972
Card Set
dextrose.txt
Description
Prehospital Medication Flashcards for Paramedic School - Massachusetts and Rhode Island
Updated
4/3/2011, 5:18:22 PM
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