dextrose.txt

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Dextrose 50% (D50)

Trade Name
- Dextrose
- D50
- D50W
- Glucose
Dextrose 50% (D50)

Class
- Carbohydrate
- Hypertonic Solution
Dextrose 50% (D50)

Mechanism of Action
- Rapidly increases serum glucose levels.
- Short-term osmotic diuresis
Dextrose 50% (D50)

Indications
- Hypoglycemia
- Altered Level of Consciousness
- Coma of Unknown Etiology
- Seizure of Unknown Etiology
- Status Epilepticus (controversial)
Dextrose 50% (D50)

Contraindications
- Intracranial Hemorrhage
- Delirium Tremens
- Ineffective Without Thiamine (?)
Dextrose 50% (D50)

Adverse Reactions
- Extravasation leads to tissue necrosis
- Warmth
- Pain
- Burning
- Thrombophlebitis
- Rhabdomyositis (rare form of cardiomyopathy)
Dextrose 50% (D50)

Drug Interactions
- Sodium bicarbonate
- Coumadin
Dextrose 50% (D50)

How Supplied

25 gm/ 50 ml pre-filled syringes (500 mg/ml)
Dextrose 50% (D50)

Dosage and Administration
Adult

12.5-25 gram slow IV; may be repeated as necessary
Dextrose 50% (D50)

Dosage and Administration
Pediatric
- 0.5-1 gm/kg/dose slow IV; may be repeated as necessary
- D10%: 0.5 gm/kg IV Bolus (for neonates)
- D25%: 0.5 gm/kg IV Bolus (if estimated body weight < 50kg)
- D50%: 0.5 gm/kg IV Bolus (if estimated body weight> 50 kg)
Dextrose 50% (D50)

Duration of Action
- Onset: less than 1 minute
- Peak effects: Variable
- Duration: Variable
Dextrose 50% (D50)

Special Considerations
- Administer thiamine prior to D50 in known alcoholic patients
- Draw blood sugar before administering
- Do not administer to patients with known CVA unless hypoglycemia documented

Author:	papeirce
ID:	76972
Card Set:	dextrose.txt
Updated:	2011-04-03 17:18:22
Tags:	paramedic medications drugs prehospital dextrose
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Description:	Prehospital Medication Flashcards for Paramedic School - Massachusetts and Rhode Island
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