lorazepam.txt

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Author:
papeirce
ID:
77133
Filename:
lorazepam.txt
Updated:
2011-04-03 22:21:33
Tags:
paramedic medications drugs prehospital lorazepam ativan
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Description:
Prehospital Medication Flashcards for Paramedic School - Massachusetts and Rhode Island
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  1. Lorazepam

    Trade Name
    Ativan
  2. Lorazepam

    Class
    • Benzodiazepine
    • Sedative-Hypnotic
    • Anticonvulsant
  3. Lorazepam

    Mechanism of Action
    • Anxiolytic
    • Anticonvulsant and sedative effects
    • Suppresses propagation of seizure activity produced by foci in cortex, thalamus and limbic areas
  4. Lorazepam

    Indications
    • Management of seizures
    • Adjunct to cardioversion & pacing (sedation)
  5. Lorazepam

    Contraindications
    • Acute narrow-angle glaucoma.
    • Coma
    • Shock
    • Suspected drug abuse
  6. Lorazepam

    Adverse Reactions
    • Respiratory depression
    • Apnea
    • Drowsiness
    • Sedation
    • Ataxia
    • Psychomotor impairment
    • Confusion
    • Restlessness
    • Delirium
    • Hypotension
    • Bradycardia
  7. Lorazepam

    Drug Interactions
    May precipitate CNS depression if patient is already taking CNS depressant medications
  8. Lorazepam

    How Supplied
    2 and 4 mg / ml concentrations in 1 ml vials
  9. Lorazepam

    Dosage and Administration
    Adult
    2-4 mg slow IV/IO at 2 mg/min. or IM; may repeat in 15-20 minutes to maximum dose of 8 mg

    Note: When given IV or IO, must dilute with equalvolume of sterile water or sterile salineWhen given IM, Lorazepam is not to be diluted
  10. Lorazepam

    Dosage and Administration
    Pediatric
    0.05 -0.20 mg/kg slow IV, IO slowly over 2 minutes or IM; may repeat in 15-20 minutes to maximum dose of 0.2 mg/kg

    Note: When given IV or IO, must dilute with equalvolume of sterile water or sterile salineWhen given IM, Lorazepam is not to be diluted
  11. Lorazepam

    Duration of Action
    • Onset of action: 1-5 minutes
    • Peak effect: variable
    • Duration of action: 6-8 hours
  12. Lorazepam

    Special Considerations
    • Pregnancy safety: Category D
    • Monitor BP and respiratory rate during administration
    • Have advanced airway equipment readily available
    • Inadvertent arterial injection may result in vasospasm and gangrene
    • Lorazepam expires in 6 weeks if not refrigerated

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