ch 17 continued

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Author:
jackiedh
ID:
77340
Filename:
ch 17 continued
Updated:
2011-04-04 22:38:11
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pharmacology continued
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Description:
ch 17
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  1. COX inhibitors may only be used for pain management with which agent?
    CCBs (it is contraindicated for all other groups)
  2. stroke, MI, and hypertension are effects of _______ levels
    cholesterol
  3. the total cholesterol level in a healthy patient will be < ______ mg/dl
    200
  4. LDL should be < ______mg/dl to be healthy
    130
  5. HMG-CoA reductase inhibitors are used to _______ ________
    lower cholesterol
  6. which inhibitor is referred to a "statins"?
    HMG-CoA reductase inhibitors
  7. lipitor, zocar, restor, and lescol are all which type of agent?
    lipid-lowering agents
  8. how do lipid-lowering agents work?
    they interfere with cholesterol synthesis in the liver
  9. cholestyramine, colesevelam, and colestipol are all ______ ______sequestrants
    bile acid (lipid-lowering agents)
  10. what is the mechanism of action of bile acid sequestrants (cholestyramine, colesevelam, colestipol)?
    agents bind with bile in intestine and form insoluble complex
  11. bile acid sequestrants may be used in combination with ________ ________ inhibitors
    HMG-CoA reductase inhibitors
  12. what are used to lower cholesterol and tryglycerides and increase HDL levels?
    fibric acid derivatives
  13. lopid and tricor are both ______ _______ derivatives
    fibric acid
  14. what is the mechanism of action inhibits synthesis and increase clearance of LDLs and reduce triglycerides by decreasing hepatic extraction of free fatty acids?
    fibric acid derivatives
  15. HMG-CoA reductase inhibitors
    Bile acid sequestrants
    Fibric acid derivatives
    Niacin
    These are all _______ ______ agents
    lipid lowering
  16. what percentages does niacin reduce in:
    LDL
    triglycerides
    HDL
    • LDL=10-20%
    • triglycerides=30-70%
    • HDL=20-35%
  17. niaspan is an example of ______
    niacin
  18. what should be done when taking niacin to avoid upset GI tract?
    take drug WITH meals
  19. ezetimibe, ezetimibe and simvastatin, and plant stanol ester food products are all _____ ______ agents
    lipid lowering agents
  20. which 3 agents are used for long term prevention and treatment of angina pectoris?
    • isosorbide dinitrate
    • isosorbide mononitrate
    • CCBs
  21. amyl nitrate and nitroglycerin are both _____ _______ agents for angina pectoris
    fast acting
  22. what does nitroglycerin do?
    VASODILATE!
  23. isosorbide mononitrate or dinitrate are both used to prevent and treat angina caused by _____ and are NOT the first choice of drugs
    CAD
  24. T/F pt's with CAD can recieve care if 4 MET is met
    true
  25. when is the best time to schedule someone with angina pectoris?
    • early morning
    • short appts
  26. if a patient is experiencing MI, what should be administered after contacting EMS?
    provide oxygen and 325 mg aspirin
  27. xerostomia, gingival enlargement and blood dycrasias are all ADEs of ________ agents
    antiarrhythmic
  28. an antiarrhythmic agent + ________ increases CNS effects when anesthetic is used
    propafenone
  29. t/f vasoconstrictors may interact adversely with digoxin and nonselective beta-adrenergic blocking drugs
    true

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