Neuro Pharmacology

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Author:
sweetlin82
ID:
77895
Filename:
Neuro Pharmacology
Updated:
2011-04-06 19:51:43
Tags:
neuro pharm
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Description:
N250 Test 4
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  1. Dilantin
    Classification?
    Therapeutic Level?
    Adverse Effects?

    Cautions?
    Administration?
    • Classification: Antiseizure
    • Therapeutic level: 10-20
    • Caution: with pregnancy, birth contro, can cause CV effects (dysrhythmia, hypotension - need cardiac monitor)
    • Adverse effects: S-J syndrome, toxic epidermal necrosis
    • Administration: no faster than 50 mg/min, must use inline micron filter. Can only be mixed with normal saline. Never mix with another drug.
  2. Tegretol
    Classification?
    Therapeutic level?
    Adverse effects?
    Cautions?
    • Classification: Antiseizure
    • Therapeutic level: 4-12
    • Adverse effect: bone marrow suppression, SJ syndrome, epidermal necrosis
    • Cautions: with pregnancy, take with food
  3. Depakote
    Classification?
    Therapeutic level?
    Adverse effects?
    Cautions?
    • Classification: antiseizure
    • Therapeutic level: 50-100
    • Adverse effects: hepatotoxicity
    • Cautions: with pregnancy
  4. Lamictal
    Classification?
    Therapeutic level?
    Adverse effects?
    Cautions?
    • Classification: antiseizure
    • Therapeutic level: 1-5
    • Adverse effect: S-J syndrome, epidermal necrosis
    • Cautions: with pregnancy
  5. Topamax
    Classification?
    Adverse effect?
    Off label use?
    • Classification: antiseizure
    • Adverse effect: can cause closed-angle glaucoma - blindness!!!!
    • Off label use: neuropathic pain
  6. Valium and Ativan
    Classification?
    Use?
    • Classification: antiseizure
    • Use: SHORT TERM ACUTE episodes

    Valium for STATUS EPILEPTICUS
  7. Keppra
    Classification?
    Adverse effects?
    • Classification: antiseizure
    • Adverse effect: psychosis and hallucinations
  8. Neurontin
    Classification?
    Adverse effects?
    Off label use?
    • Classification: anti-seizure
    • Adverse effect: drowsiness and dizziness (DO NOT OPERATE HEAVY MACHINERY!)
    • Off label use: pain
  9. Phenobarbitol
    Classification?
    Therapeutic level?
    Adverse effetcs?
    Cautions?
    • Classification: anti-seizure
    • Therapeutic level: 10-40
    • Adverse effects: liver dysfunction, cognitive impairment
    • Cautions: with pregnancy and oral contraceptives
  10. Decadron dexamethazone
    Classification?
    Use?
    • Classification: corticosteroid
    • Use: to decrease cerebral edema, brain tumors, and swelling
  11. Mannitol
    Classification?
    Use?
    Adverse effects?
    Nursing implications?
    • Classification: osmotic
    • Use: for head injury, head bleed, before or during neuro surgery to draw free water from brain eliminated through kidneys
    • Adverse effects: renal failure, CHF, pulmonary edema, hyper/hypokalemia, hyper/hyponatremia
    • Nursing: monitor VS, CVP, resp status, urine output, neuro status, electrolyte imbalance
  12. Levodopa/Carbidopa (Sinemet)
    Classification?
    Effect?
    • Classification: anti-parkinson
    • Effect: levodopa crosses bbb. Carbidopa boosts effect of levodopa
  13. Parlodel and Requip
    Classification?
    Use?
    Side effect?
    • Classification: anti-Parkinson
    • Use: first agent used for younger patients before levodopa
    • Side effect: postural hypotension

    REQUIP: SUDDEN SLEEP EPISODES!
  14. Artane and Cogentin
    Classification?
    Side effects?
    • Classification: anticholinergic (for PD)
    • Side effects: hypotension and urinary retention
  15. Comtan and Tasmar
    Classification?
    Side effects?
    • Classification: COMT Inhibitor (for PD)
    • Side effects: neuroleptic malignant syndrome and hypotension
  16. Eldepryl
    Classification?
    Adverse effect?
    Avoid with?
    Nursing implication?
    • Classification: MAOB-I (for PD)
    • Adverse effect: hypertensive crisis (220/110)
    • Avoid with tricyclic antidepressants, SSRIs, Prozac, Demerol, foods with thyramine (aged chhese, cured meats, red wine)
    • Nursing implication: increase fluid intake because can cause dry mouth
  17. Tensilon
    Use?
    Have what available?
    • Use: to diagnose Myesthenia Gravis - should have result in 30 seconds - relieve or muscle weakness and ptosis for 5 mins
    • Have: Atropine available because can cause bradycardia
  18. Mestinon
    Classification?
    Use?
    Important to know?
    Give what for overdose?
    • Classification: anticholinesterase (for MG)
    • Use: to increase muscle strength
    • Important to know: give at regularly scheduled intervals before meals
    • Give: Atropine for overdose
  19. Imuran
    Classification?
    Adverse effect?
    • Classification: cytotoxic agent (for MG)
    • Adverse effect: hepatotoxic, immunosuppressant
  20. Interferon
    Classification?
    Adverse effects?
    • Classification: DMT (for MS)
    • Adverse effect: immunosuppressant, causes flu-like symptoms
  21. Copaxone
    Classification:
    Side effect?
    • Classification: for MS
    • Side effect: injection site reaction that should subside in 20 mins
  22. Baclofen
    Classification?
    Side effect?
    Cautions?
    • Classification: anti-spasmotic (for MS)
    • Side effect: drowsiness
    • Caution: DON'T STOP ABRUPTLY - can cause paranoia, hallucinations, and RHABDO

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