Card Set Information
HRT PHPR524 Test6
What are the sx of menopause?
Insomnia and fatigue
Decrease in sexual function
What is the tx for hot flashes?
estrogen at the lowest dose that controls the sx
continue for 3-5yrs
What is the tx for genitourinary atrophy?
Nonprescription agents (replens)
What are the benefits of estrogen in HRT?
Relieves hot flashes
Relieves genitourinary atrophy
Reduces hip fractures
Reduces vertebral fractures
Lowers LDL, increases HDL
Relieves insomnia and fatigue
Relieves mood changes
Improves sexual function
What are the risks of estrogen in HRT?
Increased risk of endometrial cancer
Increased risk of breast cancer
Increased risk of CV outcomes
What are the benefits of progestin in HRT?
Decrease risk of estrogen-induced irregular bleeding, endometrial hyperplasia, and carcinoma
What are the risks of progestin in HRT?
Unpredictable bleeding for first 8-12 months
What type of HRT is most appropriate for women with a hysterectomy?
Unopposed estrogen (conjugated estrogen only)
What is the disadvantage to Estrogen plus cyclic progestin in HRT?
Regular menses every month until tx is d/c
What is the advantage of estrogen plus continuous progestin in HRT?
Menses only lasts for first 8-12mo of tx
What are the other tx options for hot flashes?
Gabapentin (most effective, but not most used)
Clonidine (most effective, but not most used)
Clonidine patch (most effective, but not most used)
Venlafaxine (most used and help mood changes)
Fluoxetine (most used and help mood changes)
Paroxetine (most used and help mood changes)