GU & Renal Drugs

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Author:
xjessicax3
ID:
7845
Filename:
GU & Renal Drugs
Updated:
2010-02-24 13:17:37
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Pharm test 2
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Pharm test 2
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  1. Carbonic Anhydrase Inhibitors

    -Carbonic _______ is an enzyme found in_______ and_______ which extracts water from carbonic acid.
    -Inhibiting the enzyme will lead to excretion of _______ ,_______ , _______ .
    -Used to treat _______ -angle (____ ___ ) not used in _______ angle.
    • Carbonic Anhydrase Inhibitors
    • -Carbonic anhydrase is an enzyme found in kidney and lungs which extracts water from carbonic acid.
    • -Inhibiting the enzyme will lead to excretion of na, k, hc03.
    • -Used to treat open-angle (chronic glaumona) not used in narrow angle.
  2. Carbonic Anhydrase Inhibitors


    -Can be alternated with __________
    -can cause __________, __________, __________.
    -contraindicated in the _______________
    Carbonic Anhydrase Inhibitors


    • -Can be alternated with loop diuretics
    • -can cause kidney stones, metabolic acidosis , crystalluria.
    • -contraindicated in the first trimester of pregnancy
  3. Potassium Sparing Diuretics

    -_______ diuretics and can be used in combo with another _______ for max effect.
    -_______ of potassium - doesn't require _______
    -act on _______
    -should be discontinued if serum k is _______
    -Patient should put out at least _______
    Potassium Sparing Diuretics

    • -Mild diuretics and can be used in combo with another diuretic for max effect.
    • -No loss of potassium - doesn't require supplement
    • -act on collecting duct
    • -should be discontinued if serum k is >5.3 mEq/L
    • -Patient should put out at least 600ml/24hrs
  4. Potassium Sparing Diuretics

    -Prototype:________
    -Acts by antagonizing ________
    -takes up to ________ to act
    -main side effect is________ -must be monitor
    -must be used with caution in renal dysfunction
    • Potassium Sparing Diuretics
    • -Prototype:Aldactone
    • -Acts by antagonizing aldosterone
    • -takes up to 48 hours to act
    • -main side effect is increase k -must be monitor
    • -must be used with caution in renal dysfunction
  5. Renal Failure and Diuretics


    -The most commonly used drug in patients with ________ are diuretics.
    -Other medications are used to manage some of the __________________
    Renal Failure and Diuretics


    • -The most commonly used drug in patients with renal dysfunction/failure are diuretics.
    • -Other medications are used to manage some of the electrolyte imbalances
  6. Contrast Neuropathy

    -Currently, __________ is used to protect kidneys against the development of contrast induced __________
    -__________ is an oxygen radial scavenger to prevent ischemic rperfusion injury.
    -__________ are given beginning on the day prior to the procedure.
    Contrast Neuropathy


    • -Currently, Mucomyst is used to protect kidneys against the development of contrast induced nephrotoxicity
    • -Mucoyst is an oxygen radial scavenger to prevent ischemic reperfusion injury.
    • -4 doses are given beginning on the day prior to the procedure.

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