C, inbred, monoclonal antibiodies, Th2 based response, ulcerative blepharitis and periorbital abcessation, tumors later in life
CB, inbred, agouti, retinal deg and autoimmune thyroiditis (Hashimoto's Disease)
C3, agouti, LPS resistant only, alopecia areata, on atherogenic diet don't devlop disease, no MMTV but can develop mammary tumors, Pde6brd1 homozygous, hepatomas in males
B6, tumor and disease resistant, microphthalmia, hydrocephalus, preference for sweet tastes and alcohol, incisor malocclusion
B10, production for histocompatibility complex in congenics, dermatitis, hydrocephalus and eye abnormalities, preference for sweets and alcohol 30% incidence of lymphoma
D1, dilute brown non-agouti, high incidence of mammary tumors and hearing loss at 10 mos., used in rheumatoid arthritis and nephritis
D2, first inbred strain, intolerance to morphie and alcohol, audiogenic seizures -used to test anticonvulsants
SJL (Swiss Jim Lambert)
J, inbred, albino, EAE, pelvic girdle muscular dystrophy, get Hodgkins reticular cell sarcomas, rd, males very aggressive
SW, albino, inbred, EAE, mammary tumor, rd, nephrogenic DI with age
white bellied agouti chinchilla, pink eyed chinchilla, inbred, used for ES for Knockout mice, incidence of testicular teratomas
Black Kaliss, Black, inbred
Used for background strain of Leprdb LepobProgressive hearing loss by 3 mo
Brown, inbred, atherosclerotic diet, vestibular and hearing deficits, progressive hearing loss at 7 weeks, fast learner
Leaden gray, inbred, diet induced atherosclerosis and gall stones, EAE, Hodgkins like Lymphoma, 3 months hearing loss
FVB/N (Friend Virus B virus)
albino, large pronuclei, asthma like hyperresponsiveness, squamous cell carcinomas induction
High activity, anxiety, basal body temp, hypertermia, leukemia after 1 year, retinal deg.
CD-1, CFW or Swiss Webster (SW)- ideal pseudopregnant recipients for black and agoutis, NMRI, CF-1, Black Swiss-nuture fosters well, ideal pseudopreg recipient for albino, testing germline for 129 ES and C57 chimeras
Coronavirus causes what as an animal model?
myocarditis and cardiomyopathy for congestive heart failure
Main clostridial species implicaqted in the diarrhea and enterophathy of rabbits
C. spiriforme (g+) anaerobe
This anatomical structure in the rabbit serves as lymphoid tissue and is a thickening at the ilealcecal junction
This anatomical feature in the rabbit allows digesta through the cecum from the ileum
Dutch belted rabbits with this disease develop lesions similar to what human disease?
0157:H7 EHEC, hemolytic Uremic Syndrome (HUS)
What two areas should be cultured for diagnosis of P. multocida in the rabbit?