Card Set Information

2011-04-10 22:55:54
pharmacology DCTC

ch 19-28-29-30
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  1. drugs that stimulate the respiratory center of the brain and cardiovascular system
  2. drugs used to treat children with ADHD
  3. drugs used to suppress the appetite
  4. analeptics action:
    • increases the depth of respiration by:
    • stimulating chemoreceptors in the carotid arteries and upper aorta
  5. most widely used CNS stimmulants is
  6. analeptics that is used to treat narcolepsy
    • armodafinil: nuvigil
    • modafinil: provigil
  7. _____________ are sympathomimetic drug sthat stimulate CNS
  8. amphetamines results in:
    • elevation of BP
    • wakefulness
    • increase or decrease heart rate
  9. a condition successfully treated by amphetamines
  10. anorexiants are _______ and pharmacologically similar to amphetamines
    nonamphetamine drug
  11. anorexiants have the ability to ___________
    suppress appetite
  12. caffeine use:
    • fatigue
    • drowsiness
    • respiratory depression
    • adjunct in analgesic formulation
  13. amphetamine/ dextroamphetamine trade name:
  14. amphetamine/ adderall use:
    • narcolepsy
    • ADHD
  15. amphetamines adverse reaction:
    • insomnea
    • nervousness
    • headache
    • tachycardia
    • anorexia
    • dizziness
    • excitement
  16. methylphenidate trade name:
    • concerta
    • ritalin
    • metadate
    • methylin
    • daytrana (transdermal patch)
  17. dextroamphetamine trade name:
    • dexedrine
    • dextrostat
  18. dextroamphetamine use:
    • narcolepsy
    • ADHD
  19. methlyphenidate use:
    • ADHD
    • narcolepsy
  20. methylphenidate adverse reaction:
    • insomnia
    • anorexia
    • dizziness
    • headache
    • abdominal pain
  21. phendimetrazine trade name:
  22. phendimetrazine use:
  23. adverse reaction:
    • insomnia
    • nervouseness
    • headache
    • palpitaion
    • tachycardia
    • dry mouth
    • dizziness
    • excitement
  24. CNS stimulants are contraindicated in patients with:
    • hypersensitivity
    • convulsive disorders
    • ventilation disorder (COPD)
  25. CNS stimulants are not to be administered to patients with:
    • cardiac problems
    • hypertension
    • hyperthyroidism
  26. ____________ and ___________ should not be taken concurrently or within 14 days of antidepressant medication
    • amphetamines
    • anorexiants
  27. _________ and ________ have abuse and addiction potential
    • amphetamine
    • anorexiants
  28. when CNS stimulant is prescribed for respiratory depression, it is important that the nurse must:
    note the depth and pattern of respiratory rate
  29. when amphetamine is prescribed for ADHD the nurse must:
    observe various patterns of abnormal behavior
  30. after administering an analeptic,the nurse monitors:
    • respiratory rate and pattern
    • LOC
    • BP
    • pulse
  31. after adminestering analeptic, BP and pulse rate is checked every:
    • 5 to 15 minutes
    • or as ordered
  32. when CNS stimulants causes insomnia the nurse will:
    • administer the drug early in the morning
    • encourage not to take nap in middle of the day
  33. when CNS stimulants are administered, VS are checked every
    6 to 8 hours
  34. ______________ may be worsened in older adults when CNS stimulants are taken
    cardiovascular disorders
  35. when analeptic drug is used, when must the oxygen be administered?
    • before
    • during
    • after---administration
  36. use of analeptic drug enhances breathing pattern without:
    changing the effect of opiod
  37. in ADHD amphetamines are administered :
    • in the morning 30-45 minutes before breakfast and before lunch
    • dont give drug in late afternoon
  38. a specific pathologic changes occur in the cortex of the brain which involves degeneration of nerves
    Alzheimer's Disease
  39. three stages of Alzheimer's Disease:
    • early
    • middle
    • late
  40. __________ stage is typically the longest stage of Alzheimer's
  41. one of the most debilitating sysmptoms of AD and this involves a decrease in cognitive functioning
  42. ____________ are approved to treat mild to moderate dementia caused by AD
    cholinesterase inhibitors
  43. cholinesterase act to:
    • increase level of acetylcholine in the central nervous system
    • ( by inhibiting itas breakdown and slowing neural destruction.)
  44. cholinesterase use:
    to treat early and moderate stages of dementia d/t AD
  45. ginseng is also known as:
    king of herbs
  46. the primary use of ginseng is:
    to improve energy and mental performance
  47. Ginseng is contraindicated in individuals with:
    • hypertension
    • during pregnancy
  48. Gingko use:
    • to improve memory and brain function
    • enhance circulation to the brain, hear, limbs
  49. gingko contraindications:
    • Pt's taking:
    • MAOIs
    • anticoagulants
  50. abrupt dc of tacrine may cause:
    a decline in cognitive functioning
  51. a group of symptoms involving motor movement
  52. most common of parkinsonism
    Parkinson's Disease
  53. Parkinson's Disease S/SX:
    • slurred speech
    • mask-like face
    • difficulty chewing or swallong
    • unsteady gait
    • shuffled gait
    • upper body bent forward
  54. drugs used to treat sx associated with parkinsonism are called
  55. blood-brain barrier
    a meshwork of tightly packed cells in the walls of the brain's cappilaries that screen out certain substances
  56. ___________ with __________ allows more levodopa to reach the brain and permits drug to have better pharmacologic effect
    • levodopa
    • carbidopa
  57. amantadine trade name:
  58. amantadine/ symmentrel use:
    • Parkinson's disease
    • prevention and treatment of influenza A infection
    • drug induced EPS
  59. carbidopa trade name:
    • sinemet
    • parcopia
    • carbilev
  60. carbidopa/levodopa use:
    parkinson's disease
  61. benzotropin trade name:
  62. benzotropin/cogetin use:
    • parkinso n's disease
    • drug induced EPS
  63. entacapone trade name:
  64. entacapone/comtan use:
    adjunct to levodopa in parkinson's disease
  65. dopamine receptor agonist administration:
    • not to be taken P.O.
    • by transdermal patch
  66. dopaminergic use:
    • TX s/sx of parkinson's disease
    • viral infections
  67. most serious adverse reaction of levodopa:
    • choreiform movements
    • dystonic movements
  68. involuntray muscular twitching of the limbs or facial muscle
  69. muscular spasms most often affecting the tongue, jaw, eyes and neck
    dystonic movements
  70. levodopa contraindications:
    • patients with glaucoma
    • patient with unusual skin lesions
  71. pt's are screened for unusual skin lesions beofre taking levodopa because:
    levodopa can activate malignant melanoma
  72. foods high in ______ reduce efect of levodopa
    pyridoxine/ B6
  73. when levodopa is combined with _________ b6 has no effect on action of levodopa
  74. cholonergic blocking drug action:
    block ACh, which enhances dopamine transmission
  75. cholinergic blocking drug use:
    • adjunct therapy in all forms of parkinsonism
    • in the control of drug indiced extraplyramidal disorder
  76. individuals of ____ of age frequently develops increased sensitivity to anticholinergic drugs.________ dose may be requiered
    • 60
    • lower
  77. failure of the muscles of the lower esophagus to relax, causing difficulty swallowing)
  78. COMT use:
    adjunct to levodopa/carbidopa
  79. COMT action:
    thought to prolong effect of levodopa by blocking an enzyme COMT which eliminates dopamine
  80. COMT use:
    adjunct to levodopa/ carbidopa
  81. dopamine receptor agonist action:
    • not fully understood
    • mimicking effect of dopamine in the brain
  82. dopamine receptor agonist adverse reaction:
    • nausea
    • dizziness
    • abnormal involuntary movements
  83. Neuromuscular Evaluation observes for the ff:
    • hand tremors
    • masklike expression
    • speech pattern
    • drooling
    • changes in thought process
    • changes in walking
    • ability to carry out ADLs
  84. do not abruptly discontinue use of the ______________ drugs, a _________ may occur.
    • antiparkinsonism
    • neuroleptic malignant-like syndrome
  85. a sudden involuntary contraction of the muscles of the body, often accompanied by loss of consiousness
  86. periodic distuirbances of the brains electrical activity
  87. permanent recurrent seizure disorder
  88. most common type of epileptic seizure
    partial seizures
  89. seizure that arise in localized area in the brain ans cause specific symptoms
    partial seizure
  90. seizure that involves loss of consiousness
    generalized seizures
  91. ___________ seizures include alternate contraction and relaxation of muscles, loss consiousness, and abnormal behavior
    tonic-clonic seizures
  92. involves sudden forceful contractions of single or multiple groups of muscles
    myclonic seizure
  93. anticonvulsants are:
    drugs used to manage seizure disorders
  94. categories of anticonvulsants:
    • hydantoins
    • carboxylic acid derivatives
    • succinimides
    • oxazolidinediones
    • barbiturates
    • benzodiazepines