Card Set Information
What risk groups should be treated based on a > 5mm TST?
close TB contacts
What risk groups should be treated based on a > 10mm TST?
Recent US immigrants from TB areas (asia, africa, russia, E. europe, L. America)
IV drug user
Frequenters of population dense areas
Children < 4
Minors exposed to high-risk adults
What risk groups should be treated based on a > 15mm TST?
Those with no known factors for TB
Who is a close TB contact?
Recenr/prolonged exposere to known/suspected TB.
What are factors for TB transmission?
Infectiousness of TB
Type of envirnonment exposed
Duration of exposure
Virulency of bacilli
How should close TB contacts be handled?
evaluated for LTBI and TB disease
+ TST/IGRA --> LTBI Tx
- TST/IGRA --> retest in 8-10 weeks
When can you start TB treatment on close contacts with a negative TST/IGRA?
Less than 8-10 weeks have passed since exposure:
Children < 5
Living with HIV
What is the progression of TB treatment?
Initial Phase - 8 wks = 4 drugs used
Continuation Phase - > 8 wks = drugs used
What's the initial regimine for TB?
Isoniazid, Rifampin, Pyrazinamide, Ethambutol
What are benefits of QFT-G test over TST?
Only 1 pt visit
Results in 24 hrs
No booster phenomenon
Less likely incorrect reading
No BCG FP
What are disadvantages of QFT-G testing?
Samples must be processed in 12 hrs
Errors in running/interpreting test
Limited data for minors, immunosuppresive, HIV, blood disorders
What's the basis for the QFT-G test?
Blood samples mixed with Ag for 16-24 hrs
Blood cells recognized Ag and release IFN-g
Results based on amount of IFN-g released